Inflammation and course themes
Download
1 / 44

Inflammation and Course Themes - PowerPoint PPT Presentation


  • 95 Views
  • Uploaded on

Inflammation and Course Themes. Nancy Long Sieber, Ph.D. Sept. 14, 2009. Challenges and Adaptation. http://www.usc.edu/hsc/dental/PTHL312abc/312a/02/Graphics/figure01.gif. http://www.siumed.edu/~dking2/crr/images/CR007b.jpg. What is the significance of injury and toxicity?.

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about ' Inflammation and Course Themes' - aqua


An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
Inflammation and course themes

Inflammation and Course Themes

Nancy Long Sieber, Ph.D.

Sept. 14, 2009


Challenges and adaptation
Challenges and Adaptation

http://www.usc.edu/hsc/dental/PTHL312abc/312a/02/Graphics/figure01.gif



What is the significance of injury and toxicity
What is the significance of injury and toxicity?

  • Tissues differ in their capacity for repair

    • Epithelial cells are continuously replaced

    • Nerve cells, in general, do not divide

  • Organs also differ in their “safety factors”

    • All organs have some amount of excess capacity

    • With aging and injury, the excess capacity is lost, and this may lead to loss of function


http://www.wirednewyork.com/hotels/marriott_marquis/images/marriott_marquis_elevators.jpghttp://www.wirednewyork.com/hotels/marriott_marquis/images/marriott_marquis_elevators.jpg


Elevator cable for passenger elevatorshttp://www.wirednewyork.com/hotels/marriott_marquis/images/marriott_marquis_elevators.jpg

has a safety factor of about 11

http://www.gkivdo.com/gkii/wire_3.jpg


Necrosis and Apoptosishttp://www.wirednewyork.com/hotels/marriott_marquis/images/marriott_marquis_elevators.jpg

http://pubs.niaaa.nih.gov/publications/arh25-3/image01.gif


Developing human hand before web apoptosis
Developing human hand before http://www.wirednewyork.com/hotels/marriott_marquis/images/marriott_marquis_elevators.jpgweb apoptosis

http://www.i-am-pregnant.com/img/day48-hand.gif


Developing hand after web apoptosishttp://www.wirednewyork.com/hotels/marriott_marquis/images/marriott_marquis_elevators.jpg

http://www.grg.org/breakingnews2001.htm


Modified from: http://www.chrononhotonthologos.com/inactive/strokedr/hbothera.htm


Inflammation
Inflammation http://www.chrononhotonthologos.com/inactive/strokedr/hbothera.htm

http://www.uic.edu/classes/bios/bios100/lecturesf04am/inflammation01a.jpg


Inflammation http://www.chrononhotonthologos.com/inactive/strokedr/hbothera.htm

Pro-inflammatory cytokines

IL-1 IL-6 TNF

Positive acute phase reactants:

LIVER

Haptoglobin

C3

Fibrinogen

Serum amyloid A

C-reactive Protein


Http www easterncarolinaent com allergy triggers copy jpg
http://www.easterncarolinaent.com/Allergy-Triggers-copy.jpg http://www.chrononhotonthologos.com/inactive/strokedr/hbothera.htm

Common Allergens


Http www euromeds co uk allergy treatment information htm

http://www.euromeds.co.uk/allergy-treatment-information.htm http://www.chrononhotonthologos.com/inactive/strokedr/hbothera.htm

Allergen binds to IgE, which links to mast cells, triggering release of histamine.


Autoimmune disease
Autoimmune Disease http://www.chrononhotonthologos.com/inactive/strokedr/hbothera.htm

http://www.mctd.eu/images/AutoimmuneDisorder.jpg


Http www wellesley edu chemistry chem227 nucleicfunction cancer cancer html

Cancer http://www.chrononhotonthologos.com/inactive/strokedr/hbothera.htm

http://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.html


Http www wellesley edu chemistry chem227 nucleicfunction cancer cancer html1
http://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.htmlhttp://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.html


Stress responses
Stress Responseshttp://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.html


Obesity trends among u s adults brfss 1985
Obesity Trends* Among U.S. Adultshttp://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.htmlBRFSS, 1985

(*BMI ≥30, or ~ 30 lbs overweight for 5’ 4” person)

No Data <10% 10%–14%

www.cdc.gov


http://www.cancer.gov/cancertopics/factsheet/Risk/obesityhttp://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.html


Obesity trends among u s adults brfss 1986
Obesity Trends* Among U.S. Adultshttp://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.htmlBRFSS, 1986

(*BMI ≥30, or ~ 30 lbs overweight for 5’ 4” person)

No Data <10% 10%–14%


Obesity trends among u s adults brfss 1987
Obesity Trends* Among U.S. Adultshttp://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.htmlBRFSS, 1987

(*BMI ≥30, or ~ 30 lbs overweight for 5’ 4” person)

No Data <10% 10%–14%


Obesity trends among u s adults brfss 1988
Obesity Trends* Among U.S. Adultshttp://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.htmlBRFSS, 1988

(*BMI ≥30, or ~ 30 lbs overweight for 5’ 4” person)

No Data <10% 10%–14%


Obesity trends among u s adults brfss 1989
Obesity Trends* Among U.S. Adultshttp://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.htmlBRFSS, 1989

(*BMI ≥30, or ~ 30 lbs overweight for 5’ 4” person)

No Data <10% 10%–14%


Obesity trends among u s adults brfss 1990
Obesity Trends* Among U.S. Adultshttp://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.htmlBRFSS, 1990

(*BMI ≥30, or ~ 30 lbs overweight for 5’ 4” person)

No Data <10% 10%–14%


Obesity trends among u s adults brfss 1991
Obesity Trends* Among U.S. Adultshttp://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.htmlBRFSS, 1991

(*BMI ≥30, or ~ 30 lbs overweight for 5’ 4” person)

No Data <10% 10%–14% 15%–19%


Obesity trends among u s adults brfss 1992
Obesity Trends* Among U.S. Adultshttp://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.htmlBRFSS, 1992

(*BMI ≥30, or ~ 30 lbs overweight for 5’ 4” person)

No Data <10% 10%–14% 15%–19%


Obesity trends among u s adults brfss 1993
Obesity Trends* Among U.S. Adultshttp://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.htmlBRFSS, 1993

(*BMI ≥30, or ~ 30 lbs overweight for 5’ 4” person)

No Data <10% 10%–14% 15%–19%


Obesity trends among u s adults brfss 1994
Obesity Trends* Among U.S. Adultshttp://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.htmlBRFSS, 1994

(*BMI ≥30, or ~ 30 lbs overweight for 5’ 4” person)

No Data <10% 10%–14% 15%–19%


Obesity trends among u s adults brfss 1995
Obesity Trends* Among U.S. Adultshttp://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.htmlBRFSS, 1995

(*BMI ≥30, or ~ 30 lbs overweight for 5’ 4” person)

No Data <10% 10%–14% 15%–19%


Obesity trends among u s adults brfss 1996
Obesity Trends* Among U.S. Adultshttp://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.htmlBRFSS, 1996

(*BMI ≥30, or ~ 30 lbs overweight for 5’ 4” person)

No Data <10% 10%–14% 15%–19%


Obesity trends among u s adults brfss 1997
Obesity Trends* Among U.S. Adultshttp://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.htmlBRFSS, 1997

(*BMI ≥30, or ~ 30 lbs overweight for 5’ 4” person)

No Data <10% 10%–14% 15%–19% ≥20%


Obesity trends among u s adults brfss 1998
Obesity Trends* Among U.S. Adultshttp://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.htmlBRFSS, 1998

(*BMI ≥30, or ~ 30 lbs overweight for 5’ 4” person)

No Data <10% 10%–14% 15%–19% ≥20%


Obesity trends among u s adults brfss 1999
Obesity Trends* Among U.S. Adultshttp://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.htmlBRFSS, 1999

(*BMI ≥30, or ~ 30 lbs overweight for 5’ 4” person)

No Data <10% 10%–14% 15%–19% ≥20%


Obesity trends among u s adults brfss 2000
Obesity Trends* Among U.S. Adultshttp://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.htmlBRFSS, 2000

(*BMI ≥30, or ~ 30 lbs overweight for 5’ 4” person)

No Data <10% 10%–14% 15%–19% ≥20%


Obesity trends among u s adults brfss 2001
Obesity Trends* Among U.S. Adultshttp://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.htmlBRFSS, 2001

(*BMI ≥30, or ~ 30 lbs overweight for 5’ 4” person)

No Data <10% 10%–14% 15%–19% 20%–24% ≥25%


Obesity Trends* Among U.S. Adultshttp://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.htmlBRFSS, 2002

(*BMI ≥30, or ~ 30 lbs overweight for 5’ 4” person)

No Data <10% 10%–14% 15%–19% 20%–24% ≥25%


Obesity trends among u s adults brfss 2003
Obesity Trends* Among U.S. Adultshttp://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.htmlBRFSS, 2003

(*BMI ≥30, or ~ 30 lbs overweight for 5’ 4” person)

No Data <10% 10%–14% 15%–19% 20%–24% ≥25%


Obesity trends among u s adults brfss 2004
Obesity Trends* Among U.S. Adultshttp://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.htmlBRFSS, 2004

(*BMI ≥30, or ~ 30 lbs overweight for 5’ 4” person)

No Data <10% 10%–14% 15%–19% 20%–24% ≥25%


Obesity trends among u s adults brfss 2005
Obesity Trends* Among U.S. Adultshttp://www.wellesley.edu/Chemistry/chem227/nucleicfunction/cancer/cancer.htmlBRFSS, 2005

(*BMI ≥30, or ~ 30 lbs overweight for 5’ 4” person)

No Data <10% 10%–14% 15%–19% 20%–24% 25%–29% ≥30%


http://www.lipidsonline.org/slides/slide01.cfm?q=abdominal+fat&pg=1http://www.lipidsonline.org/slides/slide01.cfm?q=abdominal+fat&pg=1


http://mednews.wustl.edu/tips/page/normal/8947.htmlhttp://www.lipidsonline.org/slides/slide01.cfm?q=abdominal+fat&pg=1


The women in this study did not gain weight but they did have an increase in abdominal fat
The women in this study did not gain weight, but they did have an increase in abdominal fat

http://www.lipidsonline.org/slides/slide01.cfm?q=abdominal+fat&dpg=10


ad