RESPIRATORY HEALTH & ENVIRONMENT SUMMIT For Life and Breath: Allergies, Asthma, and the Environment Panel "Clearing Airways: Creating Asthma and Allergy Friendly Homes, Schools and Workplaces" John Molot MD CCFP FCFP. What is good IAQ?.
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RESPIRATORY HEALTH & ENVIRONMENT SUMMIT For Life and Breath: Allergies, Asthma, and the Environment Panel "Clearing Airways: Creating Asthma and Allergy Friendly Homes, Schools and Workplaces" John Molot MD CCFP FCFP
Indoor Air Quality Guide. ASHRAE 2009
Do we really have good IAQ?
Lancet 2002 Oct 19;360(9341):1203-9
Boothe VL. J Environ health. 2008 Apr;70(8):33-41
Major road = 10,000 vehicles/24 hr
Influence could be additiveor synergistic
Present ventilation standards and guidelines:
modest requirement that the indoor air shall be acceptable to 80% of occupants.
not based on health effects
Current building codes, standards and guidelines:
based primarily on practical experience within the building sector
based on non-health related criteria such as perceived acceptability of air
does not consider other contaminants.
Contents: PM, VOCs, SVOCs, other chemicals, O3, biologicals
*surfaces enhance effective reaction rates
Indoor pollutants react with each other.
occurs either in the gas phase or on surfaces
large surface area compared to outdoors
walls, floors, carpets, furnishings
skin and respiratory tract (breathing zone)
oxygenation (ozone) reactions, acid-base reactions, hydrolysis reactions, and decomposition reactions
major source of free radicals and other short-lived reactive species in indoor environments
Carreiro-Martins P. EurJ Pediatr. 2014 Mar 4. (ahead of print)
Exposures to volatilized components of water-based paint, water-based cleaning products, glass cleaning, oven cleaning, dish-washing, and the use of chlorine bleach significantly increases the risks of acute asthma, and other acute respiratory symptoms.
ChoiH. IntJ Environ Res Public Health. 2010 Dec;7(12):4213-37.
Who is susceptible?
Islam T. Glutathione-S-transferase (GST) P1, GSTM1, exercise, ozone and asthma incidence in school children. Thorax. 2009; 64(3):197-202.
Romieu I. GSTM1 and GSTP1 and respiratory health in asthmatic children exposed to ozone. EurRespir J. 2006 Nov;28(5):953-9.
McCunney RJ. Asthma, genes, and air pollution. J Occup Environ Med. 2005; 47(12):1285-91
Fatani SH. Biomarkers of oxidative stress in acute and chronic bronchial asthma. J Asthma. 2014 Mar 19. (ahead of print)
Hope J.ScientificWorldJournal. 2013 Apr 18;2013:767482.
Kim JH. Ind Health 2011;49(1):8-14
Improvement of IAQ by a factor of 2–7 compared with existing standards:
Something is wrong with present standards