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Scale-up of Programmatic MDR TB Management (PMTM) in the Philippines

Scale-up of Programmatic MDR TB Management (PMTM) in the Philippines. ROSALIND G. VIANZON, MD, MPH NTP Manager Department of Health Philippines. Magnitude of MDRTB in the Philippines:. Treatment Failure Rate (Smear +), NTP. Treatment Failure* Rate (Smear +) DOTS Center at MMC .

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Scale-up of Programmatic MDR TB Management (PMTM) in the Philippines

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  1. Scale-up of Programmatic MDR TB Management (PMTM) in the Philippines ROSALIND G. VIANZON, MD, MPH NTP Manager Department of Health Philippines

  2. Magnitude of MDRTB in the Philippines:

  3. Treatment Failure Rate (Smear +), NTP

  4. Treatment Failure* Rate(Smear +) DOTS Center at MMC * All turned out to be MDR-TB

  5. Stages of PMTM in the Philippines Pilot Stage: • Goes beyond DOTS  “DOTS (+)” • Initial Scope and context – GLC Pilot Project • Privately Initiated DOTS Unit at MMC as the starting point “DOTS (+) Project at MMC ” • 75% referrals from: Private practitioners • PPMD: need to harness PPs into DOTS • Laboratory capacity for culture and DST • 2nd line drugs need to be secured and assured • Sustainability - impending concern

  6. Stages of PMTM in the Philippines Stage of Mainstream: • Integration of DOTS(+) into the public DOTS • Stepwise implementation • “LCP DOTS (+) Project”- public counterpart • - in-house services • Referrals from both public and private MDs • Community-based approach: Decentralize to public health centers with participation from community volunteers • Absorptive Capacity – prevailing concern

  7. Cohort Outcome 1999-2004 n=281

  8. Stages of PMTM in the Philippines Stage of Scale-up: • Expansion of Project into Program (PMTM) • Geographic expansion (Region: Metro Manila) • Engaging more community-based facilities - PPMD units (Public and Private-initiated) - Public DOTS Hospitals (District Hospitals) - Other Public Health Centers • More decentralized approach - realistic, viable • Added complexity and financial demand

  9. R2 Mainstream R5 Scale-up

  10. PPMD Unit at MMC (Privately-Initiated) Microscopy DOTS NTP PUBLIC Facility (1st line drugs)

  11. Evolution of a PPMD Unit into a DOTS-Plus unit Microscopy Culture DST DOTS PUBLIC Facility (1st line drugs) DOTS Plus

  12. Mainstream into the Public DOTS Treatment Site (Health Center) Treatment Site (Health Center) Microscopy Treatment Site (Health Center) Culture DST Microscopy Culture LCP DOTS(+) Treatment Center KASAKA DOTS(+) Treatment Center DOTS DOTS Plus PUBLIC Facility (1st line drugs) Microscopy Culture Treatment Site (Health Center)

  13. 8 Treatment Centers 4 Culture Centers 3 DST Sites MORE Treatment Sites CEBU The Scale-up

  14. Types of PMTM Facilities Treatment Centers: - more than 10 patients being treated at a time - more comprehensive/specialized management (e.g. LCP, KASAKA-QI) Treatment Sites: - fewer patients (<10) being treated at a time - represented by public health centers, PPMDs other public facilities, faith-based DOTS units

  15. Types of PMTM Facilities Microscopy Culture Culture Centers: - perform culture services, NTRL supervises EQA - broader catchment areas - those identified under the DRS e.g. Cebu Ref. Lab. DST Sites: - perform DST, NTRL oversees quality of culture and microscopy - fewer but strategically located (2 Manila, 1 Cebu) - under the supervision of supranational laboratory Microscopy Culture DST

  16. DOTS is STILL the OVERARCHING FRAMEWORK Political commitment Quality microscopy service Regular availability of 1st line drugs D.O.T Standardized records and reports 1. Sustained political commitment. 2. Diagnosis of drug resistance through quality-assured culture and drug susceptibility testing (DST). 3. Uninterrupted supply of quality assured second-line anti-TB drugs. 4. Appropriate treatment strategies utilizing DOT with second-line drugs under proper management conditions. 5.Recording and reporting system designed for DOTS-Plus programs.

  17. Steps and Requirements for the SCALE-UP • Environmental scanning * Existing resources and capacities - DRS * For strategic selection of expansion sites • Advocacy to ensure political commitment * Memorandum of Understanding (MOU) • Create essential organizational structures * PMTM Task Force, PMTM Consillium, Lab. SubCommittee

  18. Steps and Requirements for the SCALE-UP • Policies, guidelines, standards development • Human resource development * Task Analysis * Standardized training materials • Network of lab services and other diagnostics * Microscopy, EQA, Culture and DST * Chest X-ray with TBDC participation

  19. HRH Capacity-Building Training of Trainers Training for Monitoring and Supervision Training for Implementers Training (Region) Monitoring & Supervision (Province/City) DOTS-Plus Implementation Treatment Center DOTS-Plus Implementation Treatment Site

  20. Supranational Laboratory Scale-up of Laboratory Capacity NTRL & Other DST Sites DST Culture EQA Microscopy Regional TB Reference Laboratory PHO/CHO Validation Center DOTS-Plus Implementation Treatment Center

  21. Steps and Requirements for the SCALE-UP • Logistics management: *2nd line drugs, 1st line drugs and drugs for adverse reactions Selection NTP,TDF Utilization Tx Centers, Tx Sites Drug Cycle for 2nd Line Drugs Procurement TDF,GLC,WHO Distribution NTP, CHDs, LGUs

  22. Steps and Requirements for the SCALE-UP • Community involvement to facilitate a decentralized approach * Treatment Centers * Treatment Sites • Public-Private Partnership- engaging PPMD units. Private physicians need to be harnessed to the DOTS strategy to prevent them from proliferating MDRTB.

  23. Steps and Requirements for the SCALE-UP • Standardized information/data system * Records and Reports • Monitoring, Supervision and Evaluation * Internal MSE * External MSE - GLC

  24. Steps and Requirements for the SCALE-UP • Access potential agencies for support Government (National and Local) Non-Government Agencies, Private sector External Assistance (Technical and Financial) GFATM, USAID, WHO, Others • Address the 5 dimensions of sustainability: Political*Technological*Sociocultural*Economic/Financial Institutional

  25. MDR Cases and Scaling-upApproach – Impact Relationship XDR Undetected MDRs With Appropriate Management Scale-up Program Approach (PMTM) Mainstream LCP Project Pilot MMC DOTS (+) Project

  26. THANK YOU

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