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Answer. 1.Alder- reilly anamoly . 2. plasma cells 3. Burkett lymphoma “starlight” 4. Chediak-Steinbrinck –Higashi Anomaly 5. Reed sternberg cells- Hogdkin lymphoma 6. Smudge cells –CLL/SLL 7. ALL 8. AML 9. May- Hegglin Anomaly, associated with giant platelets

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  1. Answer • 1.Alder- reillyanamoly. • 2. plasma cells • 3. Burkett lymphoma “starlight” • 4. Chediak-Steinbrinck –Higashi Anomaly • 5. Reed sternberg cells- Hogdkin lymphoma • 6. Smudge cells –CLL/SLL • 7. ALL • 8. AML • 9. May-Hegglin Anomaly, associated with giant platelets • 10. hairy Cell lymphoma-B cell • 11. Sezary- t cell • 12. Dsyelomyeloiesis • 13. Pelger-Huet Bodies • 14. Nuclear extrusion anomaly • 15. Dohle bodies • 16.Promyelocyte • 17. Band • 18. Myelocyte • 19.metamyelocyte • 20. Auer rods

  2. Alder-Reilly Anomaly 1.Cytoplasmic inherited abnormalities of neutrophils. 2. Seen in inherited Hunter’s or Hurler’s syndromes. 3. Heavy granulation. 4. Also seen in mucopolysaccharide storage disease. 5. Caused by an inherited autosomal recessive trait.

  3. May-Hegglin Anomaly Rare, autosomal dominant, qualitative leukocyte abnormality. Appears as Dohle-like inclusions. Associated with giant platelets , thrombocytopenia , and slight bleeding tendency. Cytoplasmic inclusions in May-Hegglin anomaly are PAS negative. Inclusion found in eosinophils, basophils, monocytes, and neutrophils. Cytoplasmic inclusions results from structural RNA.

  4. Chediak-Steinbrinck –Higashi Anomaly Rare, autosomal recessive disorder that results in qualitative abnormalities in all types of leucocytes. Giant , coarse , irregular , peroxidase positive lysosome granules are found in the cytoplasm of granulocytes and monocytes. Patients demonstrate abnormal pigmentation ,pancytopenia, neuropathies, and recurrent infections.

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