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Transgenic Animals. By: Amber, Catherine, Kayla, Lauren. What is a transgenic animal ?. A transgenic animal is animal whose chromosomes have been changed to carry the genes of other organisms . How are (they) transgenic animals made ?.

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transgenic animals

Transgenic Animals

By: Amber, Catherine, Kayla, Lauren

what is a transgenic animal
What is a transgenic animal?
  • A transgenic animal is animal whose chromosomes have been changed to carry the genes of other organisms.
how are they transgenic animals made
Howare(they) transgenic animals made?
  • There are three main ways to produce transgenic animals: microinjection, blastocyst injection, and the help of a retrovirus.
microinjection
Microinjection:
  • This involves injecting a trangene, the gene used to create a transgenic animal, into a fertilized egg.
  • There is little ability to determine where the transgenic is located and whether it will survive.
  • Because of this, most eggs do not survive or do not have the transgene, but between 1% and 30% of the eggs injected can produce a live transgenic animal.
blastocyst injection
Blastocyst Injection:
  • This involves placing the transgene into an embryonic stem cell or ES cell.
  • ES cells are cells that are able to develop into all types of tissues.
  • The cells are injected into blastocysts, which is an early stage of development. The injected ES cells become part of the animal and the animal becomes a mixture of transgenic and original cells.
help of a retrovirus
Help of a Retrovirus:
  • A retrovirus is a virus that can insert itself into a host’s chromosomes.
  • This virus is inserted into the cells.
  • The animals that contain the virus must breed to produce a transgenic animal.
why are they transgenic animals being made
Why are (they)transgenic animals being made?
  • Transgenic animals are being made to help economic traits, be used as disease models, and help in medical research.
economic traits
Economic Traits:
  • Scientists created cattle to produce milk containing certain human proteins which may help in the treatment of emphysema.
  • It also helps in breeding. Farmers can produce transgenic animals that have the needed traits for doing a specific job.
disease models
Disease Models:
  • Scientists are creating animals with specific human diseases and cancers, so that they can study the affects it has on the body. They hope this will help them find a cure for the different diseases and cancers.
medical research
Medical Research:
  • Every year people die because of lack of a replacement heart,liver, or kidney.
  • Transgenic pigs may be able to supply these organs.
  • Research is trying to find a way to remove a pig protein and replace it with a human protein.
credits
Credits
  • Info from:
    • Transgenic Animals by Dag Marcus Eide
    • The Virtual Embryo
    • Action Bioscience
  • Pictures from:
    • RNC Home
    • Green Florescent Protein
    • Belligerati
    • Living the Scientific Life
    • Geocities
    • Matching Making
    • Zoological Sciences
    • Gurdon Institute
    • Guelph
    • Pittsburg Development Center
    • Papilio
    • EnviroZine
    • 2 Day Blog
    • University Animal Care
    • BBC
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