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Νόσος των λεγιοναρίων Λεγιονέλλωση PowerPoint PPT Presentation


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Νόσος των λεγιοναρίων Λεγιονέλλωση. Αναγνωρίσθηκε το 1976. Πώς μεταδίδεται. Μικρόβιο που φιλοξενείται στο νερό Αερογενώς μεταδιδόμενο νόσημα με σταγονίδια ή εισρόφηση. Που οφείλεται. Αίτιο: Legionellae (48 είδη) Σύνηθες είδος: L. pneumofila (90%),

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Νόσος των λεγιοναρίων Λεγιονέλλωση

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1976


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: Legionellae (48 )

  • : L. pneumofila (90%),

  • To L. anisa ,

  • L.longbeachae ( )


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, , , ,

5-6

5-28%


Pontiac

PONTIAC

  • : 5-66


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  • CDC 1000 , 25.000 , 4000 .

  • 0.6-12% 1%


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: , (3-5 ) 42-48% 100%

() 66% -90% ( 1) ( 5-10 )

(1 ),

IFA () 10-15 (gG<1:128 IgM.< 256) 92%. 95% ( 1 L pneumophila)

(1 ),

, 3-6


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DFA 2-10 , (20%) (100%)

PCR 55 R 80%(6-10 ) , 100%.


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Winthrop- University Hospital Criteria

78% 65%

  • (, , , )

  • -

  • , , ,


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  • ().


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;

,


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  • 70 - 80 C :

  • 66 C : 2

  • 60 C : 32

  • 55 C : 5 -6

  • > 50 C :

  • 35 -46 C :

  • 20 -50 C :

  • < 20 C :


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:

,


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:

40- 60%

57% 21% (1995)

6 Km!!


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:

  • ()

  • 60 C

  • 60 C

  • ,spas


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  • (1981) . cases-controls .


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70%.


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;

  • ,

  • 9% ( )


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European Working Group on Legionella

1986 (DIP slides)

, 30 C 48 .

.


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  • To , , .


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7-10 .


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  • : 1-4

  • , 15 2 6 , < 10CFU/ml (OSHA)


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, , 0 cfu/ml


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  • ( )

  • ()

  • , , DBNPA

  • ,


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60 C () 50 C


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