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1. Modeling the Cholera Outbreak in Haiti: a Multi-patch Disease Model Leah Campbell
Steve Fassino
Kyle Frank
Michael Kelly
Shishi Luo
Rachel Taylor
2. Cholera Infection of the small intestine caused by bacterium Vibria cholerae
Transmission is primarily through consumption of contaminated drinking water or food
Person-to-person transmission very rare
Estimated 3-5 million Cholera cases and 100,000 to 120,000 deaths due to Cholera per year
4. SIWR Model
5. Analytical approach
6. Example: 3-patch hub system
9. Parameter dependence
10. Contribution to R0Haiti from I High betaI for satellites has larger impact on R0 compared to high BetaI for Ouest. The quantity of satellites with large infected rates outweighs the contribution of movement into Ouest.High betaI for satellites has larger impact on R0 compared to high BetaI for Ouest. The quantity of satellites with large infected rates outweighs the contribution of movement into Ouest.
11. Small gamma=larger R0
Higher hub and low other satellites produces low R0
While lower hub and higher other satellites produces high R0Small gamma=larger R0
Higher hub and low other satellites produces low R0
While lower hub and higher other satellites produces high R0
12. Disease dynamics
15. Conclusion
16. Thanks to:
MBI-NIMBioS-CAMBAM
Marisa Eisenberg
Joe Tien