true religion genes
Download
Skip this Video
Download Presentation
True Religion Genes

Loading in 2 Seconds...

play fullscreen
1 / 31

True Religion Genes - PowerPoint PPT Presentation


  • 106 Views
  • Uploaded on

True Religion Genes. A Guide to Jewish Genetics Kaitlin Medland. Genetic Diseases in General. All Ethnic Groups: Cystic Fibrosis, Fabry Diease , Fragile X Syndrome, Prader-Willi Syndrome, Spinal Muscular Atrophy, WHIM Syndrome. African American: Beta-Thalassemia, Sickle Cell Anemia.

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about ' True Religion Genes' - amandla


An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
true religion genes

True Religion Genes

A Guide to Jewish Genetics

Kaitlin Medland

genetic diseases in general
Genetic Diseases in General

All Ethnic Groups:

Cystic Fibrosis, FabryDiease, Fragile X Syndrome, Prader-Willi Syndrome, Spinal Muscular Atrophy, WHIM Syndrome

African American:

Beta-Thalassemia, Sickle Cell Anemia

Asian:

Alpha-Thalassemia, Beta-Thalassemia, Kawasaki Disease

ashkenazi or sephardi
Ashkenazi or Sephardi

Ashkenazi:

Ancestors came from France, Germany, or Eastern Europe

Sephardi:

Ancestors came from Spain, Portugal, North Africa, and the Middle east

genetic disorders seen in sephardi populations
Genetic Disorders Seen in Sephardi Populations
  • Beta Thalassemia
  • Familial Mediterranean Fever
  • G6PD Deficiency
  • Glycogen Storage Disease, Type III
  • Wolman Disease
genetic disorders seen in ashkenazi populations
Genetic Disorders Seen in Ashkenazi Populations
  • Bloom’s Syndrome 1 in 110
  • Canavan Disease 1 in 57
  • Cystic Fibrosis 1 in 25
  • Familial Dysautonomia 1 in 30
  • Familial Hyperinsulinism 1 in 66
  • Fanconi Anemia Group C 1 in 89
  • Gaucher Disease, Type 1 1 in 12
  • Glycogen Storage Disease, Type 1 1 in 72
  • Joubert Syndrome 2 1 in 92
  • Maple Syrup Urine Disease 1 in 81
  • Mucolipidosis IV 1 in 100
  • Nemaline Myopathy 1 in 108
  • Niemann-Pick Disease, Type A 1 in 90
  • Spinal Muscular Atrophy 1 in 41
  • Tay-Sachs Disease 1 in 26
  • Usher Syndrome 1F- 1 in 141

(Type 1F and Type III) Type III- 1 in 107

  • Walker-Warburg Syndrome 1 in 149
  • Dihydrolipoamide 1 in 96

Dehydrogenase Deficiency

  • Hereditary Cancers
focus for today
Focus for Today
  • The four genetic disorders we will be focusing on today are:
    • Cystic Fibrosis
    • Familial Dysautonomia
    • Tay-Sachs Disease
    • Hereditary Cancer
cystic fibrosis
Cystic Fibrosis
  • Stems from respiratory and GI tracts
  • Early development delays
  • Seizures
  • Treatment Options:
    • Pancreatic enzymes
    • Antibiotics
    • Airway Clearance
    • Lung Transplantation for some
familial dysautonomia
Familial Dysautonomia
  • Inability to regulate sensory and autonomic nervous system
  • Cardiovascular, pulmonary, and GI problems
  • Treatment Options:
    • Management of symptoms
    • Supportive care
tay sachs disease
Tay-Sachs Disease
  • Rapid and progressive deterioration of the brain and nervous system
  • Treatment Options:
    • Supportive care
    • Management of symptoms
types of testing
Types of Testing
  • Diagnostic Testing
  • Carrier Screening
  • Prenatal Testing
  • Predictive Testing
  • Pre-Implantation Genetic Diagnosis
  • Direct to consumer genetic testing
what happens next
What Happens Next?

Egg Donor

Adoption

Sperm Donor

Carrier

25% Chance

Pre-implantation genetic Diagnosis

tay sachs in o ther populations
Tay-Sachs in Other Populations
  • 1 in 50 Irish-Americans
  • 1 in 250 from the general public
hereditary cancer
Hereditary Cancer
  • Ashkenazi Jews are at a higher risk for types of breast, ovarian, and colon cancers
  • Predisposition genes
    • BRCA1 and BRCA2 gene mutations
slide29

Limit fat intake

  • Maintain a healthy body weight
  • Make exercise a part of daily life
  • Cut back on cocktails
  • Don’t smoke
eating right
Eating Right
  • Vitamin D
  • Vitamin A
  • Vitamin E
  • Fiber
  • Fruits and Vegetables
ad