Tsitsi g monera phd fellow ub uz aids training program
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Traditional Medicine and HIV Clinical Pharmacology: Implementation Research PowerPoint PPT Presentation


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Tsitsi G Monera, PhD Fellow UB-UZ Aids Training Program. Traditional Medicine and HIV Clinical Pharmacology: Implementation Research . Outline. Parirenyatwa Hospital OI clinic support group Support group – Researcher model Herb-drug clinical study.

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Traditional Medicine and HIV Clinical Pharmacology: Implementation Research

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Tsitsi G Monera, PhD Fellow UB-UZ Aids Training Program

Traditional Medicine and HIV Clinical Pharmacology: Implementation Research


Outline

  • Parirenyatwa Hospital OI clinic support group

  • Support group – Researcher model

  • Herb-drug clinical study


Parirenyatwa Hospital OI clinic support group

  • People with common interests and experiences

  • Safe space to share common concerns, verbalize emotions

  • Positive reinforcement, emotional support, hope

  • Learning environment –coping skills, self-help projects, treatment information


Support group Researcher

  • model born out of the HIV-infected patients’ needs for comprehensive pharmacotherapy and the pharmacologists’ needs to explore pharmacotherapy issues in HIV-Infected patients

  • mutually beneficial collaboration between support group and researcher


Prevalence of Use of Traditional Medical Systems


Traditional Medicine


Preliminary in vivo studies in animal models typically serve as a basis for clinical trials


Effect of Moringa oleifera (Moringa, Drumstick, Horseradish tree)on the Pharmacokinetics of Efavirenz and Nevirapine in vivo.


Ethical Considerations

  • To compare the steady-state pharmacokinetics of nevirapine and efavirenz in HIV-positive patients before and after supplementation with Moringa oleifera leaf powder

  • 5 challenging levels of ethical and regulatory approvals (JREC, HSIRB, BRTI- exemption) Medical Control Authority (MCAZ)and national ethics committee (MRCZ)


  • Acknowledgements

    The program is sponsored by the UB-UZ AIDS International Training Research program funded by the Fogarty International Center.


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