Tsitsi g monera phd fellow ub uz aids training program
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Traditional Medicine and HIV Clinical Pharmacology: Implementation Research PowerPoint PPT Presentation


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Tsitsi G Monera, PhD Fellow UB-UZ Aids Training Program. Traditional Medicine and HIV Clinical Pharmacology: Implementation Research . Outline. Parirenyatwa Hospital OI clinic support group Support group – Researcher model Herb-drug clinical study.

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Traditional Medicine and HIV Clinical Pharmacology: Implementation Research

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Tsitsi g monera phd fellow ub uz aids training program

Tsitsi G Monera, PhD Fellow UB-UZ Aids Training Program

Traditional Medicine and HIV Clinical Pharmacology: Implementation Research


Outline

Outline

  • Parirenyatwa Hospital OI clinic support group

  • Support group – Researcher model

  • Herb-drug clinical study


Parirenyatwa hospital oi clinic support group

Parirenyatwa Hospital OI clinic support group

  • People with common interests and experiences

  • Safe space to share common concerns, verbalize emotions

  • Positive reinforcement, emotional support, hope

  • Learning environment –coping skills, self-help projects, treatment information


Support group researcher

Support group Researcher

  • model born out of the HIV-infected patients’ needs for comprehensive pharmacotherapy and the pharmacologists’ needs to explore pharmacotherapy issues in HIV-Infected patients

  • mutually beneficial collaboration between support group and researcher


Prevalence of use of traditional medical systems

Prevalence of Use of Traditional Medical Systems


Traditional medicine

Traditional Medicine


Preliminary in vivo studies in animal models typically serve as a basis for clinical trials

Preliminary in vivo studies in animal models typically serve as a basis for clinical trials


Traditional medicine and hiv clinical pharmacology implementation research

Effect of Moringa oleifera (Moringa, Drumstick, Horseradish tree)on the Pharmacokinetics of Efavirenz and Nevirapine in vivo.


Ethical considerations

Ethical Considerations

  • To compare the steady-state pharmacokinetics of nevirapine and efavirenz in HIV-positive patients before and after supplementation with Moringa oleifera leaf powder

  • 5 challenging levels of ethical and regulatory approvals (JREC, HSIRB, BRTI- exemption) Medical Control Authority (MCAZ)and national ethics committee (MRCZ)


  • Acknowledgements

    Acknowledgements

    The program is sponsored by the UB-UZ AIDS International Training Research program funded by the Fogarty International Center.


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