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ACIDOSE

CYCLE ALANINE-GLUCOSE. Alpha cétoglutarate. Alanine. Alanine. Alpha cétoglutarate. Cycle alanine glucose. FOIE. KREBS. SGPT réversible. sgpt réversible. Exercice prolongé. Acide glutamique. LDH H4. Lactate. Pyruvate. Pyruvate. LDH M4. Acide glutamique. Selon H4/M4

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ACIDOSE

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  1. CYCLE ALANINE-GLUCOSE Alpha cétoglutarate Alanine Alanine Alpha cétoglutarate Cycle alanine glucose FOIE KREBS SGPT réversible sgpt réversible Exercice prolongé Acide glutamique LDH H4 Lactate Pyruvate Pyruvate LDH M4 Acide glutamique Selon H4/M4 Avec ou sans O2 PEPck irréversible MUSCLE Glutaminase OXALO ACETATE OXALO ACETATE PEPck irréversible PEP ATP Glutamine synthétase ATP ADP TG O2 Glutamine ADP O2 Cycle de KREBS 12ATP/cycle (énergie) GLUCOSE Glutamine (Inhibe) Glutamine - - + (Stimule) Glutaminase Cliquer une fois et laisser défiler. L’acidose d’effort Inhibe la transformation de la glutamine en acide glutamique dans le foie mais dans le rein et le muscle c’est l’effet inverse : la glutamine se transforme en acide glutamique dans le rein réduisant l’acidose. Dans le muscle,le cycle de krebs aboutit au pyruvate et Acide glutamique tranformée en glutamine puis retransformée en ac glutamique dans le rein pour éliminer des ions H+ + + Ac GLUTAMIQUE (Stimule) ACIDOSE NH4 NH3 REIN Influence du PH Fuite urinaire des ions acides H+ Sous la forme NH4+

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