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Ομοιοστασία καλίου στη ΧΝΝ PowerPoint PPT Presentation


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Ομοιοστασία καλίου στη ΧΝΝ. Γ. Τσιρπανλής Π. Λιαβέρη Νεφρολογικό Τμήμα, Γ.Ν.Α. «Γ. Γεννηματάς» Αθήνα. Χρόνια Νεφρική Νόσος (ΧΝΝ) και κάλιο. Επικρατούσα άποψη: η ΧΝΝ συνοδεύεται από υπερκαλιαιμία Κλινική εμπειρία νεφρολόγων:

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Ομοιοστασία καλίου στη ΧΝΝ

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3931331

.

.

,

... .


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()


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  • :

  • :

  • ( 5 GFR< 15 ml/min)

  • ( )


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  • 242 Pittsburg, .


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  • 66259 [2005] 245808


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  • 820 4 2,6 .


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:


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+ /


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3-5

+


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+ +

+


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+ ( )

Aldo


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: , +


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, +

2 Na+ ,

, - , +


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+(30% 10% ) ,


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() + ...

+

. . +

... + a+-K+-ATP

  • +

  • . . .

  • a+-K+-ATP +

  • . . .


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+

Na+-K+-ATP +


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+

Na+-H2O

K+ ( )

() K+


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  • Na+-H2O .


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K+

:

K+: , , , ,


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  • K+

  • - - , - , ,

  • , -

  • -


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5


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N/S 0,9%

+


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AGII AT1

  • 5-10%

  • ACEIs 2%

  • (ACEIs+ARBs): 5%

  • 0.1-0.3 mEq/L

  • H 1-5%


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;

  • , ,


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  • 66259 [2005] 245808


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  • 820 4 2,6 .


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  • ()

  • +

  • + . , Na+ H2O

  • a+-+- K+ Na+ 3

  • - K+ GFR


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  • ()

  • , + , a+-+- ,

  • + . , --, GFR, +, .


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