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Lower Extremity Malperfusion Complicating Type A Dissection: A 10-year Single Center Experience

Lower Extremity Malperfusion Complicating Type A Dissection: A 10-year Single Center Experience. KM Charlton-Ouw MD 1 , K Sritharan BA 1 , SS Leake BS 1 , HK Sandhu MD 1 , CC Miller PhD 2 , A Azizzadeh MD 1 , HJ Safi MD 1 , AL Estrera MD 1. Department of Cardiothoracic and Vascular Surgery

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Lower Extremity Malperfusion Complicating Type A Dissection: A 10-year Single Center Experience

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  1. Lower Extremity Malperfusion Complicating Type A Dissection: A 10-year Single Center Experience KM Charlton-Ouw MD1, K Sritharan BA1, SS Leake BS1, HK Sandhu MD1, CC Miller PhD2, A Azizzadeh MD1, HJ Safi MD1, AL Estrera MD1 Department of Cardiothoracic and Vascular Surgery The University of Texas Medical School at Houston Memorial Hermann Heart & Vascular Institute1 Department Biosciences, Texas Tech University Health Science Center2

  2. 59 year old man with chest pain and left leg pain.

  3. Acute Type A dissection with occlusion of left iliac artery.

  4. Objectives • Type A aortic dissection can result in malperfusion syndromes and are associated with poorer surgical outcomes and high morbidity and mortality. • Some advocate peripheral revascularization or endovascular procedures prior to proximal aortic repair. • We analyzed our practice of urgent proximal aortic repair, with additional revascularization in face of persistent ischemia, in proximal aortic dissections complicated by lower extremity ischemia.

  5. Methods

  6. Results • 142 of 296 cases (48.0%) complicated by malperfusion syndrome (MPS) • 28 (9.5%) patients had lower extremity MPS • 5 of 28 (6.5%) LE MPS patients needed peripheral bypass.

  7. Results • 52% of LE MPS patients suffered post-operative acute kidney injury and 44% needed hemodialysis. • Cardiac tamponade was associated with 21.4% of LE MPS patients. • GFR predictive of mortality • 14.2% overall in-hospital mortality (p=ns). • 14.8% mortality with any malperfusion (p=ns). • 13.6% mortality without malperfusion (p=ns). • Highest mortality in patients with mesenteric ischemia (67%). • Lowest mortality in patients with lower extremity malperfusion (10.7%)

  8. 30-day Mortality

  9. Conclusions • Lower extremity malperfusion in acute type A dissection is not predictive of mortality. • No justification for operative delay or percutaneous peripheral revascularization. • Majority of lower extremity malperfusion resolves after proximal aortic repair.

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