بسم الله الرحمن الرحيم. B AND T LYMPHOCYTES MEDIATERS OF ADAPTIVE IMMUNE RESPONSE Dr.Mohammed Sharique Ahmed Quadri Assistant professor Physiology Al Maarefa College . Objectives. Describe the different types of lymphocytes
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بسم الله الرحمن الرحيم
B AND T LYMPHOCYTES
MEDIATERS OF ADAPTIVE IMMUNE RESPONSE
Dr.Mohammed Sharique Ahmed Quadri
Assistant professor Physiology
Al Maarefa College
Broadly there are 2 types -
I. Innate/Non-specific/Natural Immunity.
Provides first line of defense against infections.
After early childhood most new lymphocytes are derived from peripheral lymphocyte colonies rather than from bone marrow
The majority of antigens to which B cell respond are T-dependent
Composed of 4 interlinked polypeptide chains
Two long, heavy chains
Two short, light chains
Properties of tail portion determine functional properties of the antibody( what it will do after binding with antigen)
Identical antigen-binding fragments (Fab) at tip of each arm (unique for each different antibody)
Tail (constant region) regions within each subclass are identical
Formation of memory cell can occurs through the person either actually having disease or being vaccinated