Basics of Treatment of Victims of Radiation Terrorism or Accidents. Niel Wald, M.D. Dept. of Environmental and Occupational Health University of Pittsburgh. Medical Radiation Problems. External Radiation Source: Local Radiation Injury Acute Radiation Syndrome
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Niel Wald, M.D.
Dept. of Environmental and Occupational Health
University of Pittsburgh
External Radiation Source:
II Transepidermal Injury
III Dermal Radionecrosis
IV Chronic Radiodermatitis
67Ga scintigraphy; 111In-labeled anti-myosin
Three Stage Kinetic Model Accidents
Nausea Skin Erythema
Clinical Management Problems
Growth Factors: GSF, GMCF,
Stem Cell Transplants: Autografts
(Marrow, cord, PB) Isografts
Some Systemic Agents that have been used:
CONSULT INFECTIOUS DISEASE, TRANSPLANT, or HEMATOLOGY/ ONCOLOGY SPECIALISTS for BEST CURRENT THERAPY for IMMUNOSUPPRESSED PATIENTS
Routes of Entry:
Decay Rates and energies
Chemical Compounds, Solubility, Particle Size, etc.
Time and Duration
Radionuclides and Forms
FIRST AID prn. for SHOCK, BLEEDING and ACUTE RESPIRATORY DISTRESS
Removal of Contaminated Clothing
Intermediate Stage (at clean location,if necessary)
(Phosphajel or Amphojel)
Rare Earths, 143Pm, 140La, 90Y,
65Zn, 46Sc: DTPA
Advances in the Biosciences: Advances in the Treatment of Radiation Injuries. MacVittie, T.J., Weiss, J.F., and Browne, D., Pergamon Press, New York, 1996.
Medical Effects of Ionizing Radiation. 2nd Edition. Mettler, F.A.Jr, and Upton, A.C., W.B. Saunders, Philadelphia, PA, 1995.
NCRP Report No. 65, Management of Persons Accidentally Contaminated with Radionuclides. National Council on Radiation Protection and Measurements Committee, George L. Voelz, Chairman; NCRP, Washington, DC, 1980.