Overactive bladder in a tertiary centre - prevalence and assessment of risk factors

1. No. 055 Overactive bladder in a tertiary centre - prevalence and assessment of risk factors Christopher C. K. Ho, B. Bahadzor, G.H. Tan, E.H. Goh, P. Singam, M. Z. Zulkifli Urology Unit, Dept. of Surgery, UniversitiKebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia Introduction The International Continence Society (ICS) defines Overactive Bladder (OAB) as ‘urgency, with or without urge urinary incontinence (UI), usually associated with frequency and nocturia’ . Data on overactive bladder (OAB) is scarce in Malaysia. Results 400 respondents aged between 18 to 70 years were included . The overall prevalence of overactive bladder in the study population was 42%. The prevalence among females and males were 34.7% and 48.8%. The most common symptom was nocturia (85.1%). The odds of having OAB among males was found to be 1.8 times higher, smokers 1.5 times higher, family history of OAB 1.9 times higher and those having radiotherapy exposure was 2.8 times higher. Ethnicity, age, socioeconomic status, occupation, history of pelvic surgery and parity were not significantly associated with OAB. The most common complaint affecting the activity of daily living of OAB patients was sleep disturbance(43.5%). Table : Overactive bladder and associated factors Aim The objective of this study was to determine the prevalence of OAB in our unique multi-ethnic population as well as analyse the sociodemography, risk factors and the impact of OAB on quality of life. Methods A cross-sectional face-to-face community-based survey was conducted. The respondents were men and women aged between 18 to 70 years who were patients, relatives of patients and staff of our institution (except the urology clinic). 200 men and 200 women were randomly selected for this study (convenience sampling). Those who refused to participate, were unable to respond to the questionnaire accordingly; who have other obvious pathological problems, such as urinary tract infection, stones, BPH or patients who were being treated in the urology clinic were excluded from this study. The OAB Screener – OAB V8 study was used. A questionnaire was designed to collect data on participants’ socio-demographic data, impact of OAB on quality of life and associated risk factors. Written consent was also obtained from the respondents. Conclusions The prevalence of OAB is relatively high in our institution as compared to other Asian and European countries. The odds of OAB was higher among males, smokers, those with positive family history of OAB and those with history of radiotherapy. The most common impact on quality of life was sleep disturbance. References Abrams P, Cardozo L, Fall M. et al. The standardization of terminology of lower urinary tract function: report from the Standardization Sub-committee of the International Continence Society. NeurourolUrodyn. 2002; 21(2):167-78 Irwin D, Milsom I, Hunskaar S,  et al.  Population-based survey of urinary incontinence, overactive bladder, and other lower urinary tract symptoms in five countries: results of the EPIC study. Eur Urol. 2006;50:1306 Cheung WW, Khan NH, Choi KK, et al. Prevalence, evaluation and management of overactive bladder in primary care. BMC Family Practice 2009, 10:8doi:10.1186/1471-2296-10-8 Acknowledgements This research was approved by the Research and Ethical Committee, Faculty of Medicine, UniversitiKebangsaan Malaysia (FF-291-2010). Poster presentation sponsor