Management of Dengue Fever . Dr David Tran 16/09/09. Classic clinical dengue fever. Incubation period 3 to 14 days (usually 4 to 7 days) Sudden onset of fever with severe headache Retro-orbital pain, fatigue Often associated with myalgia and arthralgia
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Management of Dengue Fever
Dr David Tran
Although in some reports, the same efficiency of detection for virus of the 4 serotypes has been described for the Dengue Early ELISA and Strip tests (Dussart et al., 2008), A recent analysis of the performance of these tests in Vietnam suggests a lower sensitivity for DENV-2 compared with DENV-1 and DENV-3.
These tests in Vietnam suggests a lower sensitivity for DENV-2 compared with DENV-1 and DENV-3. Also, a decreased sensitivity for DENV-4 with the Dengue Early ELISA has been reported in studies from South America (Bessoff et al., 2008; Dussart et al., 2008).
A lower sensitivity for DENV-2 has been described in samples from Vietnam (Hang et al., 2009) tested by the PLATELIA™systems (ELISA and Strip) and belonging to the Asian genotype 1 (according to the classification of Twiddy et al., 2002).
Sensitivity of NS1 Ag detection tests according to the day of illness(Mc Bride, Diagnostic Microbiology & Infectious Diseases, 64 – 2009 – 31,36)