Challenges and successes in dairy cattle genomics. History. Why genomics works in dairy. Extensive historical data available Well-developed genetic evaluation program Widespread use of AI sires Progeny test programs High valued animals, worth the cost of genotyping
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Challenges and successes in dairy cattle genomics
Holstein and Jersey
Current sources of data
AIPLAnimal Improvement Programs Lab., USDA
CDCBCouncil on Dairy Cattle Breeding
DHIDairy Herd Improvement (milk recording organizations)
NAABNational Association of Animal Breeders (AI)
PDCAPurebred Dairy Cattle Association (breed registries)
Sources of genomic data
(Ex: AI, breeds)
Genomic Evaluation Lab
Evaluation Date (YYMM)
Net Merit ($)
Pedigree is equivalent to information on about 7 daughters
For the protein yield (h2=0.30), the SNP genotype provides information equivalent to an additional 34 daughters
What is a SNP genotype worth?
And for daughter pregnancy rate (h2=0.04), SNP = 131 daughters
a PL=productive life,CE = calving ease and SB = stillbirth.
b 2011 deregressed value – 2007 genomic evaluation.
Cole, J.B., and Null, D.J. 2012. AIPL Research Report GENOMIC2: Use of chromosomal predicted transmitting abilities. Available: http://aipl.arsusda.gov/reference/chromosomal_pta_query.html.
Milk:Feed Price Ratio
July 2012 Grain Costs
Soybeans: $15.60/bu (€0.46/kg)
Corn: $ 7.36/bu (€0.23/kg)
M:FP = price of a kg of milk /
price of a kg of a 16%
Cole, J.B., and P.M. VanRaden. 2011. Use of haplotyes to estimate Mendelian sampling effects and selection limits. J. Anim. Breed. Genet. 128(6):448-455.
Correlation = .68
Provisional US patent filed on
20 NOV 2010 after the
9WCGALP in Leipzig – no
disclosure at that time!
This MS with similar ideas was
submitted 22 SEP 2010 and
published on 12 APR 2011.