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نقش تغذيه در سندرم متابوليك PowerPoint PPT Presentation


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نقش تغذيه در سندرم متابوليك. تهيه كننده : مائده پيراسته فرد كارشناس تغذيه مركز بهداشتي و درماني امام سجاد (ع). سندرم متابولیک چیست؟. اختلال شایعی است که در آن علاوه بر چاقی،هیپرلیپیدمی و اختلال تحمّل گلوکز نیز دیده میشود.

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نقش تغذيه در سندرم متابوليك

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  • :

  • ()


  • .

  • .


- . - ( ) . .


Visceral

Obesity

Overeating

MetabolicSyndrome:TheDeadly Quintet

Camus 1966, Reaven 1988

Diabetes HypertensionHyperuricemia

Insulin Hyperinsulinemia

Resistance

  • TNF

  • Leptin

    Adiponectin

+

Exercise

PAI-1

Lipid Abnormalities

  • triglycerides

    HDL

    small dense LDL

+

Myocardial

Infarction

ALSO ASSOCIATED WITH:

MYOSTEATOSIS AND NASH


  • 3 :

  • Abdominal obesity: waist circumference, >102 cm

  • Hypertriglyceridemia: > 150 mg/dl

  • Low HDL cholesterol:<40 mg/dl in men, <50 mg/dl in women

  • High blood pressure: >130/85 mm

  • High fasting glucose: >110 mg/dl


33% (40%). (25%) 41% .


HVOs and metabolic syndrome in Iranian women

Odds ratio (per quintile)

Q2

Q3

Q4

Q5

Quintiles of HVOs intake

Esmaillzadeh and Azadbakht. Diabetes Care 2008


() . . . 2 . - .


. . :

1-

2-

3-

4-

. .


o

o ( )

o

o

o ( )

o HDL

o

o ( ) .


:

88 102 .

.


150 1/7 .

HDL 40 50 HDL .

120 80 .

110


:

:

- ( BMI 25 )

-

-

- 25 .


.


88 102 .

-

-

- .

- 200 . 1200-1000 3500 .

- 20 30 .


B6 E .

- (1% ) .

- .

- . LDL) HDL) . .


. . .

. . LDL HDL . (Metformin) .


. .



  • .

  • : .

  • : .


  • : ( ). SFA TFA . . .

  • .


  • : . SFA . EFA . .


:

Azadbakht and Esmaillzadeh. J Nutr 2009

Iran Nutrition Society, Feb 2010


  • : (use sparingly) . . .

  • . .

  • ( 10 )


Esmaillzadeh et al. Am J Clin Nutr 2007

Iran Nutrition Society, Feb 2010


Esmaillzadeh et al. Am J Clin Nutr 2007

Iran Nutrition Society, Feb 2010


.


.

( 3/1% 5/2% )


  • : )

  • )

  • )

  • )


  • :


  • : . ( ) . .


  • . .

  • . .


8 .

  • - . 2 30 90 . .

  • 8 5/3 .

  • .


.

. .


4 .

  • . 13 5 .

  • :

  • 1- .

  • 2- .

  • 3- .

  • 25 6 4 .

  • . .


.

  • . : .

  • . .


.

  • 30 60 .

  • .

  • .

  • 30 60 .


. .


. .

. (fiber-rich grains) (antihypertensive) ( ) .


Whole-grain intake and the metabolic syndrome:

a favorable association in Tehrani adults

Refined-grain intake

Whole-grain intake

Esmaillzadeh et al. EJCN 2005.

Iran Nutrition Society, Feb 2010


38 25 . . .


- ... .

. ( ) .


1- Comparison of high protein and high fiber weight loss diets

in women with risk factors for the metabolic syndrome: a

randomized trial.

2- Fermentable and non fermentable fiber supplements did not

alter hunger satiety or body weight in a pilot study of men and

women consuming self- selected diets.

3- The role of soluble fiber intake in patients under highly

4-Zabetian A, Hadaegh F, Azizi F. Relationship between

metabolic syndrome and its components with

coronary heart disease in Iranian men and women.

Experimental and Clinical Endocrinology and

5. Azizi F, Salehi P, Etemadi A, Zahedi-Asl S. Prevalence

of metabolic syndrome in an urban population: Tehran

Lipid and Glucose Study. Diabetes Res ClinPract 2003;

61: 29-37.Diabetes 2008;116(9):525-31.effective lipid lowering therapy.


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