C3H.SW TCD-BM C3H.SW Tconv (1.5x106) C3H.SW Tregs B6 OT-1

Mar 30, 2019

50 likes | 152 Views

C3H.SW TCD-BM C3H.SW Tconv (1.5x106) C3H.SW Tregs B6 OT-1. Recipient Chimeras. C3H.SW BM ->9Gy-> b 2 m -/- B6- b 2 m -/- BM -> 9Gy-> B6 B6-wt BM -> B6 (Normal). Can we test 3 cell model hypothesis. BM. BM. CD8. CD8. APC. b 2 m -/-. OT-1. CD4 FOXP3.

adie

Download Presentation

C3H.SW TCD-BM C3H.SW Tconv (1.5x106) C3H.SW Tregs B6 OT-1

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

C3H.SW TCD-BM • C3H.SW Tconv (1.5x106) • C3H.SW Tregs • B6 OT-1
Recipient Chimeras • C3H.SW BM ->9Gy-> b2m-/- • B6- b2m-/- BM -> 9Gy-> B6 • B6-wt BM -> B6 (Normal)
Can we test 3 cell model hypothesis BM BM CD8 CD8 APC b2m-/- OT-1 CD4FOXP3
How to assess stimulation/expansion of OT-1 as opposed to lymphopenic expansion • Infg • TNFa • Gzmb • Perforin • Mip1-b • pErk (Marcel Van Der Brink) • CD25