1 / 10

How do prions cause mad cow disease

How do prions cause mad cow disease. Group #5. Intro. Wendy Carrillo. What is a prion? They are not viruses, bacteria, fungi, or parasites. A protein particle that lacks nucleic acid and is sometimes held to be the cause of various infectious diseases of the nervous system e.g. scrappie.

adelle
Download Presentation

How do prions cause mad cow disease

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. How do prions cause mad cow disease Group #5

  2. Intro Wendy Carrillo

  3. What is a prion? They are not viruses, bacteria, fungi, or parasites. A protein particle that lacks nucleic acid and is sometimes held to be the cause of various infectious diseases of the nervous system e.g. scrappie. Luci Ramos-What is a prion?

  4. Maria Dominguez- • Hello

  5. Luis Rodriguez-Diff. prion diseases • Scrapie: (transmissible spongiform encephalopathy): sheep -farmers have reported cases of scrapie since the early 1700s in England, Scotland, and the US. • BSE (bovine spongiform encephalopathy): cows - first noticed in 1986 in England. Due to the similarities in the behavior of the infected cows, BSE was suspected to be linked to the common practice of feeding cattle with remnants of tissue from slaughtered sheep. • TME (transmissible mink encephalopathy): mink - found in the US • CWD (chronic wasting disease): deer, elk - found in the US • FSE (feline spongiform encephalopathy): housecats!

  6. Joe-What diseases do • They affect the brain disrupting or destroying neurons (brain cells) in large numbers, which inevitably leads to death. • Caused by prions PrP (normal/protein) infective agent protein called pRpSc. • Unknown how, but, PrPSC called protein folded improperly into more PrPSC-which then attacks brain cells.

  7. Mariano Ferraris-How prions affect proteins

  8. Andrew Griffith-Symptoms of TSE • Animal and Human ConsequencesCows infected with BSE lose weight, show abnormal behavior (skittishness), may become paralyzed and die. Humans afflicted with nvCJD begin with psychiatric problems (paranoia) or perhaps problems with their senses. They later develop problems in muscle coordination (balance, speech), muscle spasms, problems with their senses (hearing, vision) and memory loss. They may finally lapse into coma and die.

  9. Corey Wasson-Prevention • Preventive Measures • Public health control measures, such as enhanced BSE surveillance, the culling of sick animals, and bans of specified risk materials (SRM), have been instituted in countries of Europe to prevent potentially BSE-infected tissues from entering the human food chain. • In June 2000, the European Union Commission on Food Safety and Animal Welfare strengthened the European Union’s set of control measures in relation to BSE by adopting a decision requiring all member states to remove SRMs from the animal feed and human food chains as of October 1, 2000; such bans had already been instituted in most member states. • (1) avoiding beef and beef products altogether or • (2) selecting beef or beef products, such as solid pieces of muscle meat (versus calf brains or beef products such as burgers and sausages), which might have a reduced opportunity for contamination with tissues that may harbor the BSE agent. • Milk and milk products from cows are not believed to pose any risk for transmitting the BSE agent.

  10. THE END! For group five

More Related