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Complete 2013-14 Induced Pluripotent Stem Cell (iPSC) Indust

Stem cell research and experimentation has been in process for well over five decades, as stem cells have the unique ability to divide and replicate repeatedly. In addition, their “unspecialized” nature allows them to differentiate into a wide variety of specialized cell types. Browse Full Report @ http://www.aarkstore.com/healthcare/51108/Complete-2013-14-Induced-Pluripotent-Stem-Cell-iPSC-Industry-Report

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Complete 2013-14 Induced Pluripotent Stem Cell (iPSC) Indust

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  1. Category : Healthcare Complete 2013-14 Induced Pluripotent Stem Cell (iPSC) Industry Report Browse Complete Report - http://www.aarkstore.com/healthcare/51108/Complete-2013-14-Induced-Pluripotent-Stem-Cell-iPSC-Industry-Report f

  2. f Summary Stem cell research and experimentation has been in process for well over five decades, as stem cells have the unique ability to divide and replicate repeatedly. In addition, their “unspecialized” nature allows them to differentiate into a wide variety of specialized cell types. The possibilities arising from these characteristics have caused great commercial interest, with potential applications ranging from the use of stem cells in reversal or treatment of disease, to targeted cell therapy, tissue regeneration, pharmacological testing on cell-specific tissues, and more. Diseases such as Huntington’s Chorea, Parkinson’s Disease, and spinal cord injuries are examples of clinical applications in which stem cells could offer benefits in halting or even reversing damage.Traditionally, scientists have worked with both embryonic and adult stem cells as research tools. While the appeal of embryonic cells has been their ability to differentiate into any type of cell, there has been significant ethical, moral and spiritual controversy surrounding their use for research purposes. Although some adult stem cells do have differentiation capacity, it is often limited in nature, which creates narrow options for use.

  3. f Discovery: Groundbreaking experimentation in 2006 led to the introduction of induced pluripotent stem cells (iPSC). These are adult cells which are isolated and then transformed into embryonic-like stem cells through the manipulation of gene expression, as well as other methods. Research and experimentation using mouse cells at Kyoto University in Japan was the first instance in which there was successful generation of the iPSC. In 2007, a series of follow-up experiments were done at Kyoto University in which human adult cells were transformed into iPSC cells. While there has been continued excitement at the prospect of what such artificially re-manufactured cells could contribute to medical advances, there have also been issues along the way. By 2010, there were a number of private companies that were ready to capitalize on the breakthrough technology that iPSCs represent. One such company, Advanced Cell Technology in Worcester, Massachusetts, discovered several problematic issues while conducting experiments for the purpose of applying for U.S. Food and Drug Administration approval to use iPSCs in therapeutic applications. Concerns such as premature cell death, mutation into cancer cells, and low proliferation rates were some of the problems that surfaced.

  4. f Table Of Content I. ABSTRACTII. BACKGROUNDA. DefinitionB. DiscoveryC. Advantages & DisadvantagesIII. TIMELINEA. Production of iPSCs (Key Events)B. Full Timeline of Eventsnts

  5. f Table Of Content IV. RESEARCH APPLICATIONSA. Pharmaco-Toxicological ScreeningB. Disease ModelingC. Autologous Cell TransplantationD. Breakdown of iPSC Research, By Applied Research ApplicationV. CHARACTERIZATION OF iPSC RESEARCH ADVANCESA. Methods of Making iPSCs – Comparison of Methods by Downstream ApplicationB. Summary of iPSC Derivation Methods, by Cell TypeC. Diseases in Which iSPCs Have Been Derived from Patients

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  7. f Complete 2013-14 Induced Pluripotent Stem Cell (iPSC) Industry Report Published: Feb 2014 | 127 Pages Stem cell research and experimentation has been in process for well over five decades, as stem cells have the unique ability to divide and replicate repeatedly. Price

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