HUCOG - 5000 HP Injections (Human Chorionic Gonadotropin Injections)

1. HUCOG - 5000 HP Injections (Human Chorionic Gonadotropin Injections) © The Swiss Pharmacy

2. HUCOG - 5000 HP Injections (Human Chorionic Gonadotropin Injections) HUCOG - 5000 HP (Human Chorionic Gonadotropin Injections) is used in Women undergoing superovulation prior to assisted reproductive techniques such as in vitro fertilisation (IVF). HUCOG HP injection is administered to trigger final follicular maturation and luteinisation after stimulation of follicular growth. In Anovulatory or oligo-ovulatory adult women, this medicine is administered to trigger ovulation and luteinisation in anovulatory or oligo-ovulatory women after stimulation of follicular growth. In males it is used for the treatment of Prepubertal cryptorchidism not due to anatomical obstruction. In general, HCG is thought to induce testicular descent in situations when descent would have occurred at puberty. It is also used for selected cases of hypogonadotropic hypogonadism (hypogonadism secondary to a pituitary deficiency) in males. © The Swiss Pharmacy

3. HUCOG - 5000 HP Injections (Human Chorionic Gonadotropin Injections) Hucog - 5000 HP Injections, are manufactured by Bharat Serums and Vaccines Limited, India in strengths of 5000 iu of Human Chorionic Gonadotropin. © The Swiss Pharmacy

4. HUCOG - 5000 HP Injections (Human Chorionic Gonadotropin Injections) Chemical Structure © The Swiss Pharmacy

5. HUCOG - 5000 HP Injections (Human Chorionic Gonadotropin Injections) The active ingredient present in Hucog - 5000 HP HCG injection is Human Chorionic Gonadotropin. Each vial of Hucog - 5000 HP HCG injection contains 5000 iu of purified Human Chorionic Gonadotropin. © The Swiss Pharmacy

6. HUCOG - 5000 HP Injections (Human Chorionic Gonadotropin Injections) Uses of HUCOG - 5000 HP 5000iu Injections: HUCOG - 5000 HP HUCOG - 5000 HP (Human Chorionic Gonadotropin Injections) is a drug whose actions are almost the same as those of luteinizing hormone (LH), which is produced by the pituitary gland. It is a hormone also normally produced by the placenta in pregnancy. In females, chorionic gonadotropin is used to help conception occur. It is usually given in combination with other drugs such as menotropins and urofollitropin. Many women being treated with these drugs usually have already tried clomiphene alone (e.g., Serophene) and have not been able to conceive yet. Chorionic gonadotropin is also used in in vitro fertilization (IVF) programs. In males, LH and chorionic gonadotropin stimulate the testes to produce male hormones such as testosterone. Testosterone causes the enlargement of the penis and testes and the growth of pubic and underarm hair. It also increases the production of sperm. © The Swiss Pharmacy

7. HUCOG - 5000 HP Injections (Human Chorionic Gonadotropin Injections) Recommended Dosage The dosage of Hucog - 5000 HP HCG Injection Hucog - 5000 HP HCG Injection (Generic Human Chorionic Gonadotropin Injection) for various indications is given below. Dosage In The Female: Ovulation Induction In Subfertility Due To Anovulation Or Impaired Follicle- Ripening Usually, one injection of 5,000 to 10,000 IU Hucog - 5000 HP to complete treatment with an FSH- containing preparation. Preparation Of Follicles For Puncture In Controlled Ovarian Hyperstimulation Programs Usually, one injection of 5,000 to 10,000 IU Hucog - 5000 HP to complete treatment with an FS H - containing preparation. URL: https://www.theswisspharmacy.com/product_info.php?info=p9971_Hucog-5000iu-Pre-Mixed-HCG.html © The Swiss Pharmacy

8. HUCOG - 5000 HP Injections (Human Chorionic Gonadotropin Injections) Recommended Dosage The dosage of Hucog - 5000 HP HCG Injection Hucog - 5000 HP HCG Injection (Generic Human Chorionic Gonadotropin Injection) for various indications is given below. Luteal Phase Support: Two to three repeat injections of 1,000 to 3,000 IU each may be given within nine days following ovulation or embryo transfer (for example, on day 3, 6 and 9 after ovulation induction). Dosage In The Male: Hypogonadotrophic Hypogonadism: 1,000-2,000 IU Human Chorionic Gonadotropin, two to three times per week. If the main complaint is subfertility, Human Chorionic Gonadotropin may be given with an additional follitropin (FSH)-containing preparation two to three times per week. This treatment should be continued for at least three months before any improvement in spermatogenesis can be expected. During this treatment testosterone replacement therapy should be suspended. Once achieved, the improvement may sometimes be maintained by hCG alone. URL: https://www.theswisspharmacy.com/product_info.php?info=p9971_Hucog-5000iu-Pre-Mixed-HCG.html © The Swiss Pharmacy

9. HUCOG - 5000 HP Injections (Human Chorionic Gonadotropin Injections) Recommended Dosage The dosage of Hucog - 5000 HP HCG Injection Hucog - 5000 HP HCG Injection (Generic Human Chorionic Gonadotropin Injection) for various indications is given below. Delayed Puberty Associated With Insufficient Gonadotrophic Pituitary Function: 1,500 IU two to three times a week for at least six months. Cryptorchidism Not Due To Anatomical Destruction: Under 2 years of age: 250 IU twice weekly for six weeks. Under 6 years of age: 500 to 1,000 IU twice weekly for six weeks. Over 6 years of age: 1,500 IU twice weekly for six weeks. If necessary, this treatment can be repeated. URL: https://www.theswisspharmacy.com/product_info.php?info=p9971_Hucog-5000iu-Pre-Mixed-HCG.html © The Swiss Pharmacy

10. HUCOG - 5000 HP Injections (Human Chorionic Gonadotropin Injections) Contraindications ➔Hucog - 5000 HP Injections are contraindicated in patients with a known hypersensitivity to Human Chorionic Gonadotropin or any component of the tablet. ➔Known or suspected sex hormone-dependent tumours, such as ovary, breast and uterine carcinoma in female and prostatic or breast carcinoma in the male. ➔Malformations of the reproductive organs incompatible with pregnancy. ➔Fibroid tumours of the uterus incompatible with pregnancy. ➔Abnormal (not menstrual) vaginal bleeding without a known/diagnosed cause. URL: https://www.theswisspharmacy.com/product_info.php?info=p9971_Hucog-5000iu-Pre-Mixed-HCG.html © The Swiss Pharmacy

11. HUCOG - 5000 HP Injections (Human Chorionic Gonadotropin Injections) Storage Instructions HUCOG - 5000 HP Injections (Human Chorionic Gonadotropin Injections) have to be stored at controlled room temperature i.e. from 20°C to 25°C (68°F to 77°F) with excursions permitted between 15° to 30°C (59° to 86°F). Keep this as well as all other medicines away from children and pets. URL: https://www.theswisspharmacy.com/product_info.php?info=p9971_Hucog-5000iu-Pre-Mixed-HCG.html © The Swiss Pharmacy

12. HUCOG - 5000 HP Injections (Human Chorionic Gonadotropin Injections) Warnings HUCOG - 5000 HP (Human Chorionic Gonadotropin Injections) must only be administered only after the age of sexual maturity, since administration before puberty could induce undesirable stimulation of the ovaries. Induction of androgen secretion by HCG may induce precocious puberty in pediatric patients treated for cryptorchidism. HUCOG - 5000 HP (Human Chorionic Gonadotropin Injection) must only be used in conjunction with human menopausal gonadotropins only by physicians experienced with infertility problems. Before starting treatment, the couple's infertility should be assessed as appropriate and putative contraindications for pregnancy evaluated. In particular, patients should be evaluated for hypothyroidism, adrenocortical deficiency, hyperprolactinemia and pituitary or hypothalamic tumours, and appropriate specific treatment given. URL: https://www.theswisspharmacy.com/product_info.php?info=p9971_Hucog-5000iu-Pre-Mixed-HCG.html © The Swiss Pharmacy

13. HUCOG - 5000 HP Injections (Human Chorionic Gonadotropin Injections) Warnings Patients undergoing ovarian stimulation are at an increased risk of developing OHSS due to multiple follicular development. In patients undergoing induction of ovulation, the incidence of multiple pregnancy and births (mostly twins) is increased compared with natural conception. The rate of miscarriage, in both anovulatory patients and women undergoing assisted reproductive techniques, is higher than that found in the normal population but comparable with the rates observed in women with other fertility problems. Since infertile women undergoing ART, and particularly IVF, often have tubal abnormalities, the incidence of ectopic pregnancies might be increased. The incidence of congenital malformations after ART may be slightly higher than after spontaneous conceptions. In women with recent or ongoing thromboembolic disease or women with generally recognised risk factors for thromboembolic events, such as personal or family history, treatment with gonadotropins may further increase the risk for aggravation or occurrence of such events. URL: https://www.theswisspharmacy.com/product_info.php?info=p9971_Hucog-5000iu-Pre-Mixed-HCG.html © The Swiss Pharmacy

14. HUCOG - 5000 HP Injections (Human Chorionic Gonadotropin Injections) Possible Side Effects Side effects of Human Chorionic Gonadotropin Injections (HUCOG - 5000 HP Injections) include Headache, irritability, restlessness, depression, fatigue, edema, precocious puberty, gynecomastia and pain at the site of injection. Hypersensitivity reactions, both localized and systemic in nature, have been reported. URL: https://www.theswisspharmacy.com/product_info.php?info=p9971_Hucog-5000iu-Pre-Mixed-HCG.html © The Swiss Pharmacy

15. HUCOG - 5000 HP Injections (Human Chorionic Gonadotropin Injections) Overdosage An overdose of Human Chorionic Gonadotropin Injection (HUCOG HP) is not expected to produce life-threatening symptoms. Call your doctor immediately in case you have any symptoms of Ovarian hyperstimulation syndrome (OHSS): severe pelvic pain, swelling of the hands or legs, stomach pain and swelling, shortness of breath, weight gain, diarrhea, nausea or vomiting, and urinating less than normal. URL: https://www.theswisspharmacy.com/product_info.php?info=p9971_Hucog-5000iu-Pre-Mixed-HCG.html © The Swiss Pharmacy

16. HUCOG - 5000 HP Injections (Human Chorionic Gonadotropin Injections) HUCOG - 5000 HP Injections During Pregnancy Human Chorionic Gonadotropin (HUCOG - 5000 HP Injections) is classified by the US FDA as Category C. Chorionic gonadotropin may cause fetal harm when administered to a pregnant woman. Defects of forelimbs and central nervous system and alterations in sex ratio have been reported in mice receiving combined gonadotropin and chorionic gonadotropin therapy in dosages to induce superovulation. Multiple ovulations with resulting plural gestations (mostly twins) have been reported to occur in approximately 20% of pregnancies when conception has followed Chorionic Gonadotropin therapy. It is not known whether chorionic gonadotropin is excreted in human milk. Since many medicines are excreted in human milk, caution should be exercised when chorionic gonadotropin is administered to a nursing woman. URL: https://www.theswisspharmacy.com/product_info.php?info=p9971_Hucog-5000iu-Pre-Mixed-HCG.html © The Swiss Pharmacy

17. HUCOG - 5000 HP Injections (Human Chorionic Gonadotropin Injections) HUCOG - 5000 HP Injections HUCOG - 5000 HP Injections are manufactured by Bharat Serums and Vaccines Limited, India. URL: https://www.theswisspharmacy.com/product_info.php?info=p9971_Hucog-5000iu-Pre-Mixed-HCG.html © The Swiss Pharmacy