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Kevin S. Williamson Yoon Group April 9, 2009. Dolbier Jr., W.R. Journal of Fluorine Chemistry 2005 , 126, 157-163 US Patent 2230654. 2. 3. Dolbier Jr., W.R. Journal of Fluorine Chemistry 2005 , 126, 157-163. Dolbier Jr., W.R. Journal of Fluorine Chemistry 2005 , 126, 157-163

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Kevin S. Williamson

Yoon Group

April 9, 2009


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Dolbier Jr., W.R. Journal of Fluorine Chemistry 2005, 126, 157-163

US Patent 2230654

2


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Dolbier Jr., W.R. Journal of Fluorine Chemistry 2005, 126, 157-163


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Dolbier Jr., W.R. Journal of Fluorine Chemistry 2005, 126, 157-163

O’Hagan et al. Nature 2004, 427, 561-565

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Fried, J.H.; Sabo, E.F. JACS 1953, 75, 2273-74

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H.-J. Böhm et al. ChemBioChem 2004, 5, 637-643

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H.-J. Böhm et al. ChemBioChem 2004, 5, 637-643

M.A. Massa et al. Bioorganic and Medicinal Chemistry Letters 2001, 11, 1625-28

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H.-J. Böhm et al. ChemBioChem 2004, 5, 637-643


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R = H R = F

H.-J. Böhm et al. ChemBioChem 2004, 5, 637-643

Boehm et al. J. Med. Chem. 1996, 39, 3929-3937

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Tygon & Teflon

Tubing

5% F2 in N2

NaF(s)

KI traps

N2

REACTOR

Purrington, S.T.; Woodard, D.L. JOC 1991, 56, 142

Wong et al. ACIE 2005, 44, 192-212

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Wong et al. ACIE 2005, 44, 192-212

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Jørgensen et al. ACIE 2005, 44, 3703-3706


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Jørgensen et al. ACIE 2005, 44, 3703-3706


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Ball, N.D.; Sanford, M.S. JACS2009, 131, 3796-97


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Ball, N.D.; Sanford, M.S. JACS2009, 131, 3796-97


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Furuya, T.; Kaiser, H.M.; Ritter, R. ACIE 2008, 47, 5993-5996


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Furuya, T.; Ritter, T. JACS2008, 130, 10060-10061


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Furuya, T.; Strom, A.; Ritter, T. JACS 2009, 131, 1662-1663


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Furuya, T.; Strom, A.; Ritter, T. JACS 2009, 131, 1662-1663


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Phelps, M.E. PNAS 2000, 97, 9226-9233


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Top

Bottom

Prostate Cancer

Breast Cancer

30

Phelps, M.E. PNAS 2000, 97, 9226-9233




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