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Chem150 - Survey of Biochemistry. Introduction. Introduction. The chemistry we will focus on this semester Organic Chemistry The chemistry of carbon Functional groups Biochemistry The chemistry of living systems. Organic Chemistry. Organic Chemistry.

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Introduction l.jpg
Introduction

  • The chemistry we will focus on this semester

    • Organic Chemistry

      • The chemistry of carbon

      • Functional groups

    • Biochemistry

      • The chemistry of living systems



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Organic Chemistry

  • Hydrocarbons represent the starting point

    • Contain only carbon and hydrogen

    • Groups include Alkanes, alkenes and alkynes

Butane


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Organic Chemistry

  • Organic molecule are organized into functional groups

    • Many contain elements other than carbon and hydrogen

      • Oxygen

      • Nitrogen

      • Sulfur

      • Halogens (F, Cl, Br, & I)



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Organic Chemistry

  • Functional Groups

    • Hydroxyl groups (alcohols)

Hydroxyl

Group

1-Butanol


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Organic Chemistry

  • Functional Groups

    • Amino groups (amines)

Amino

Group

1-Butylamine


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Organic Chemistry

  • Functional Groups

    • Carbonyl groups (aldehydes and ketones)

Aldehyde

Group

Butanal


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Organic Chemistry

  • Functional Groups

    • Carboxyl groups (carboxylic acids)

Carboxyl

Group

Butanoic acid


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Organic Chemistry

  • Functional Groups

    • Functional group affect the physical and chemical properties of organic molecules.

Butane (alkane)

Butanol (alcohol)

Butylamine (amine)

Butanoic acid (carboxylic acid)

water

Butanal (aldehyde)


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Organic Chemistry

  • Functional Groups

    • chemical structure affects drug or hormone-receptor interactions


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Organic Chemistry

  • Functional Groups

    • Is this even possible? Or this?

http://www.ftc.gov/opa/2008/08/airborne.shtm

http://www.ftc.gov/opa/2007/08/hoodia.shtm


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Survey Question (Clicker)

  • Do you think there is some validity to HeadOn as a headache cure?

    • Yes

    • No

    • I don’t know

What chemical questions would you want to have answered to decide ?


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Survey Question (Clicker)

  • Do you have concerns about Nalgene bottles and health risks (esp to babies)?

    • Yes

    • No

    • I don’t know

What chemical questions would you want to have answered to decide ?


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Nalgene polycarbonates

What chemical questions would you want to have answered to decide ?



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PHARMACOPHORE IN THE NEWS: Bisphenol A

http://e.hormone.tulane.edu/learning/estrogens.html


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Biochemistry

  • Biological molecules

    • Amino acids and Proteins

    • Carbohydrates and Polysaccharides

    • Nucleotides and Nucleic acids

    • Lipids (Fats, oils)


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Biochemistry

  • Biological molecules

    • Aminoacids and Proteins

Carboxylic Acid

Group

Amino

Group

Alanine


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Biochemistry

  • Biological molecules

    • Carbohydrates and Polysaccharides

Glucose


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Biochemistry

  • Biological molecules

    • Lipids (Fats, oils)

Triglyceride


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Biochemistry

  • Biological Macromolecules

    • Proteins, Polysaccharides and Nucleic Acids

  • Metabolism

    • Taking things apart

    • Putting things together

  • Obtaining and using energy

  • Regulation of processes.


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