Toxicology. UNC Emergency Medicine Medical Student Lecture Series. Objectives. General approach to the poisoned patient Toxidromes Specific antidotes Decontamination and enhanced elimination. General Approach . ABC’s History Physical examination Labs, imaging Diagnosis, antidotes
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UNC Emergency Medicine
Medical Student Lecture Series
Bronchospasm GI upset
Clinical Pearl: Sweating differentiates sympathomimetic
and anticholinergic toxidromes
Magic number to remember is 140
150ug/ml at 4 hours
Rx: NAC 140mg/kg then 70mg/kg every 4 hours for 17 doses
We Have PO and IV dosing
Only useful for one time ingestion (not chronic ingestions)Need 4 hour level andN-acetylcysteine (NAC)
What do you see?
Prolonged QRS, sinus tachycardia, “tall R in R” – tall R wave in lead aVR