The body s defenses
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The body’s defenses. Lines of defense Lymphatic system Inflammation Features of immune system Memory B-cells Primary and secondary immune responses Antibody Antigen Agglutination macrophage. lymphocyte Phagocytosis Complement system Humoral immunity Cell-mediated immunity B cell

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Presentation Transcript

Reading ch 43 keywords l.jpg

Lines of defense

Lymphatic system

Inflammation

Features of immune system

Memory B-cells

Primary and secondary immune responses

Antibody

Antigen

Agglutination

macrophage

lymphocyte

Phagocytosis

Complement system

Humoral immunity

Cell-mediated immunity

B cell

Helper T cell

Cytotoxic T cell

Reading: Ch. 43; Keywords



Non specific l.jpg
Non-specific

  • First line

    • Skin

    • Mucous membranes

    • Secretions of skin and mucous membranes

  • Second line

    • Phagocytic white blood cells

    • Anti-microbial proteins

    • Inflammatory response




Focus on immune system 3rd line of defense l.jpg
Focus on immune system(3rd line of defense)

  • Protects body against specific invaders


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Key features

  • Specificity

  • Diversity

  • Memory

  • Self/Nonself Recognition




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Two types of immune responses

  • Humoral

  • Cell-mediated


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Key features

  • Specificity

  • Diversity

  • Memory

  • Self/Nonself Recognition

Humoral immunity









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Memory cells function in secondary immune response

  • Primary immune response - first exposure

  • Secondary immune response - second exposure



Summary l.jpg
Summary

  • Lag in primary response due to proliferation from a single clone

  • Secondary (2°) response is from multiple memory cells

  • 2° response has less of a lag and is stronger







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Inactivate antigens

  • Neutralization

  • Agglutination

  • Precipitation



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Antibodies inactivate antigens

  • Neutralization of invaders

  • Agglutination

  • Precipitation of soluble antigens

  • The above enhance phagocytosis

  • One final mechanism: Complement system






Summary37 l.jpg
Summary

  • Complement proteins interact with antibodies to kill invading cells

  • Binding of antibody is followed by attachment of complement proteins

  • Protein complex becomes activated

  • Pore is formed in pathogen’s membrane

  • Goodbye pathogen


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Two types of immune responses

  • Humoral

  • Cell-mediated


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Cell-mediated

  • Complicated, involves cellular components

  • Will briefly touch on role of helper T cells









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