Giant Cell Arteritis Diagnosis and Management Update

Giant Cell Arteritis Diagnosis and Management Update PowerPoint PPT Presentation


  • 231 Views
  • Updated On :
  • Presentation posted in: General

What is Giant Cell Arteritis?. Ophthalmic Emergency. .

Related searches for Giant Cell Arteritis Diagnosis and Management Update

Download Presentation

Giant Cell Arteritis Diagnosis and Management Update

An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -

Presentation Transcript


1. Giant Cell Arteritis Diagnosis and Management Update Roger Baer May 2008

2. What is Giant Cell Arteritis? Ophthalmic Emergency

3. What is Giant Cell Arteritis?

5. Diagnostic Criteria Age (=50y.o) New onset of localised headache Temporal artery tenderness or decreased temporal artery pulsation Elevated ESR (=50mm/h) Positive TAB

7. Hayreh & Zimmerman Study Opthalmologica August 2003; 217:239-259 Sohan Singh Hayreh, Bridget Zimmerman

8. Hayreh & Zimmerman Study Occult GCA 21.2% of patients with visual loss and a positive TAB had no other symptoms

9. Hayreh & Zimmerman Study Criteria Missing from ACR Guidelines Likelihood of a positive TAB were: ? 9.0 times greater if associated with jaw claudication ? 3.4 times greater if associated with neck pain ? 3.2 times greater if associated with CRP >24.5mg/l

10. Hayreh & Zimmerman Study Headache & Scalp Tenderness 55.7% of patients with a positive TAB complained of a ‘new onset of localised headache’

12. Hayreh & Zimmerman Study Clinically Abnormal Temporal Artery 19.8% of patients with a positive TAB had temporal artery tenderness or decreased temporal artery pulsation

13. Hayreh & Zimmerman Study Elevated ESR Whilst the ACR guidelines advocated an ESR of =50mm/h, this study showed a presenting ESR in patients with a positive biopsy of 4-140mm/h.

14. Hayreh & Zimmerman Study Conclusion Reliance on the ACR Guidelines is likely to result in both false-negative and false-positive diagnoses of Giant Cell Arthritis

15. Hayreh & Zimmerman Study

16. Hayreh & Zimmerman Study

17. Hayreh & Zimmerman Study

18. Hayreh & Zimmerman Study

19. Hayreh & Zimmerman Study

20. Hayreh & Zimmerman Study

21. Hayreh & Zimmerman Study

22. Hayreh & Zimmerman Study

23. Hayreh & Zimmerman Study

24. Hayreh & Zimmerman Study

25. Hayreh & Zimmerman Study Age (=55y.o) Yes, check inflammatory markers Visual symptoms? No, consider other criteria: Jaw claudication CRP >24.5mg/l Neck pain ESR >47mm/h Age =75y.o Temporal Artery Biospy

26. Hayreh & Zimmerman Study

27. Hayreh & Zimmerman Study

28. Hayreh & Zimmerman Study

29. Hayreh & Zimmerman Study

30. Hayreh & Zimmerman Study

31. Hayreh & Zimmerman Study

  • Login