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PowerLecture: Chapter 11 Observing Patterns in Inherited Traits Section 11.0: Weblinks and InfoTrac See the latest Weblinks and InfoTrac articles for this chapter online Videos: CNN Ask your Thomson Sales Representative for these volumes on CD or VHS

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Powerlecture chapter 11 l.jpg

PowerLecture:Chapter 11

Observing Patterns in Inherited Traits


Section 11 0 weblinks and infotrac l.jpg
Section 11.0: Weblinks and InfoTrac

See the latest Weblinks and InfoTrac articles for this chapter online


Videos cnn l.jpg
Videos: CNN

Ask your Thomson Sales Representative for these volumes on CD or VHS

  • Biology, 2003, Vol. 7. Tastier Tomatoes (2:53)


Impacts issues in pursuit of a better rose l.jpg
Impacts, Issues: In Pursuit of a Better Rose

  • Roses have been around for at least 40 million years

  • Researchers are working to create genetic maps for rose chromosomes




Impacts issues in pursuit of a better rose7 l.jpg
Impacts, Issues: In Pursuit of a Better Rose

  • Knowing the location of desirable genes on chromosomes helps rose breeders mix the beauty of cultivated varieties with disease resistance of wild varieties


Section 11 1 weblinks and infotrac l.jpg
Section 11.1: Weblinks and InfoTrac

See the latest Weblinks and InfoTrac articles for this chapter online


Earlobe variation l.jpg
Earlobe Variation

  • Whether a person has attached or detached earlobes depends on a single gene

  • Attached earlobes: two copies of the recessive allele for this gene

  • Detached earlobes: either one or two copies of the dominant allele


Early ideas about heredity l.jpg
Early Ideas about Heredity

  • People knew that sperm and eggs transmitted information about traits

  • Blending theory

  • Problem:

    • Would expect variation to disappear

    • Variation in traits persists


Gregor mendel l.jpg
Gregor Mendel

  • Strong background in plant breeding and mathematics

  • Using pea plants, found indirect but observable evidence of how parents transmit genes to offspring


Gregor mendel12 l.jpg
Gregor Mendel

  • The founder of modern genetics

Fig. 11-2, p.170


Slide13 l.jpg

a Garden pea flower, cut in half. Sperm form in pollen grains, which originate in male floral parts

(stamens). Eggs develop, fertilization takes place, and seeds mature in female floral parts (carpels).

b Pollen from a plant that breeds true for purple flowers is brushed onto a floral bud of a plant that breeds true for white flowers. The white flower had its stamens snipped off. This is one way to assure cross-fertilization of plants.

c Later, seeds develop inside pods of the cross-fertilized plant. An embryo within each seed develops into a mature pea plant.

d Each new plant’s flower color is indirect but observable evidence that hereditary material has been transmitted from the parent plants.

Fig. 11-3, p.170


Gregor mendel14 l.jpg
Gregor Mendel grains, which originate in male floral parts

Crossing garden pea plants


Genes l.jpg
Genes grains, which originate in male floral parts

  • Units of information about specific traits

  • Passed from parents to offspring

  • Each has a specific location (locus) on a chromosome


Alleles l.jpg
Alleles grains, which originate in male floral parts

  • Different molecular forms of a gene

  • Arise by mutation

  • Dominant allele masks a recessive allele that is paired with it


Allele combinations l.jpg
Allele Combinations grains, which originate in male floral parts

  • Homozygous

    • having two identical alleles at a locus

    • AA or aa

  • Heterozygous

    • having two different alleles at a locus

    • Aa


Genetic terms l.jpg
Genetic Terms grains, which originate in male floral parts

A pair of homologous chromosomes

A gene locus

A pair of alleles

Three pairs of genes

Figure 11.4Page 171


Slide19 l.jpg

A grains, which originate in male floral parts pair of homologous chromosomes, each in the unduplicated state (most often, one from a male parent and its partner from a female parent)

A gene locus (plural, loci), the location for a specific gene on a chromosome. Alleles are at corresponding loci on a pair of homologous chromosomes

A pair of alleles may be identical or nonidentical. They are represented in the text by letters such as D or d

Three pairs of genes (at three loci on this pair of homologous chromosomes); same thing as three pairs of alleles

Fig. 11-4, p.171


Genetic terms20 l.jpg
Genetic Terms grains, which originate in male floral parts

Genetic terms


Genotype phenotype l.jpg
Genotype & Phenotype grains, which originate in male floral parts

  • Genotype refers to particular genes an individual carries

  • Phenotype refers to an individual’s observable traits

  • Cannot always determine genotype by observing phenotype


Section 11 2 weblinks and infotrac l.jpg
Section 11.2: Weblinks and InfoTrac grains, which originate in male floral parts

See the latest Weblinks and InfoTrac articles for this chapter online


Tracking generations l.jpg
Tracking Generations grains, which originate in male floral parts

  • Parental generation P

    mates to produce

  • First-generation offspring F1

    mate to produce

  • Second-generation offspring F2


Monohybrid crosses l.jpg
Monohybrid Crosses grains, which originate in male floral parts

Experimental intercross between

two F1 heterozygotes

AA X aa

Aa (F1 monohybrids)

Aa X Aa

?


Mendel s monohybrid cross results l.jpg
Mendel’s grains, which originate in male floral parts Monohybrid Cross Results

5,474 round

1,850 wrinkled

6,022 yellow

2,001 green

882 inflated

299 wrinkled

428 green

152 yellow

F2 plants showed dominant-to-recessive ratio that averaged 3:1

705 purple

224 white

651 long stem

207 at tip

787 tall

277 dwarf

Fig. 11-6, p. 172


Slide26 l.jpg

Trait Studied grains, which originate in male floral parts

Dominant Form

Recessive Form

F2 Dominant-to- Recessive Ratio

SEED SHAPE

5,474 round

1,850 wrinkled

2.96:1

SEED COLOR

6,022 yellow

2,001 green

3.01:1

POD SHAPE

882 inflated

299 wrinkled

2.95:1

POD COLOR

428 green

152 yellow

2.82:1

FLOWER COLOR

705 purple

224 white

3.15:1

FLOWER POSITION

651 long stem

207 at tip

3.14:1

STEM LENGTH

787 tall

277 dwarf

2.84:1

Fig. 11-6, p.172


Mendel s monohybrid cross results27 l.jpg
Mendel’s Monohybrid grains, which originate in male floral parts Cross Results

Monohybrid cross


Mendel s monohybrid cross results28 l.jpg
Mendel’s Monohybrid grains, which originate in male floral parts Cross Results

F2 ratios interaction


Probability l.jpg
Probability grains, which originate in male floral parts

The chance that each outcome of a given event will occur is proportional to the number of ways that event can be reached


Monohybrid cross illustrated l.jpg

True-breeding grains, which originate in male floral parts

homozygous recessive

parent plant

F1PHENOTYPES

aa

True-breeding

homozygous dominant

parent plant

Aa

Aa

a

a

Aa

Aa

A

AA

A

Aa

Aa

Aa

Aa

An F1 plant

self-fertilizes

and produces

gametes:

F2PHENOTYPES

Aa

AA

Aa

A

a

A

AA

Aa

a

Aa

aa

Aa

aa

Monohybrid CrossIllustrated

Figure 11.7Page 173


Monohybrid cross illustrated31 l.jpg
Monohybrid Cross grains, which originate in male floral parts Illustrated

Testcross


Mendel s theory of segregation l.jpg
Mendel’s Theory grains, which originate in male floral parts of Segregation

  • An individual inherits a unit of information (allele) about a trait from each parent

  • During gamete formation, the alleles segregate from each other


Slide33 l.jpg

Homozygous dominant parent grains, which originate in male floral parts

Homozygous recessive parent

Mendel’s Theory of Segregation

(chromosomes duplicated before meiosis)

meiosis I

meiosis II

(gametes)

(gametes)

fertilization produces heterozygous offspring

Fig. 11-5, p.172


Test cross l.jpg
Test Cross grains, which originate in male floral parts

  • Individual that shows dominant phenotype is crossed with individual with recessive phenotype

  • Examining offspring allows you to determine the genotype of the dominant individual


Slide35 l.jpg

Homozygous grains, which originate in male floral parts

recessive

Homozygous

recessive

a a

a a

A

A

Aa

Aa

Aa

Aa

a

A

aa

Aa

aa

Aa

Punnett Squares of Test Crosses

Two phenotypes

All dominant phenotype


Slide36 l.jpg

Punnett Squares of grains, which originate in male floral parts Test Crosses

POSSIBLE EVENT:

PROBABLE OUTCOME:

sperm A meets egg A

sperm A meets egg a

sperm a meets egg A

sperm a meets egg a

1/4 AA offspring

1/4 Aa

1/4 Aa

1/4 aa

p.173


Slide37 l.jpg

aa grains, which originate in male floral parts

Aa

aa

a

A

a

A

A

a

A

a

A

A

A

A

Aa

AA

Aa

a

a

a

a

Aa

aa

Aa

aa

Punnett Squares of Test Crosses

female gametes

male gametes

Fig. 11-7a, p.173


Slide38 l.jpg

female gametes grains, which originate in male floral parts

male gametes

Aa

aa

a

A

a

A

A

a

A

a

Aa

AA

Aa

A

A

A

A

a

aa

Aa

aa

Aa

aa

a

a

a

Punnett Squares of Test Crosses

Stepped Art

Fig. 11-7a, p.173


Slide39 l.jpg

Punnett Squares of Test Crosses grains, which originate in male floral parts

True-breeding

homozygous recessive

parent plant

F1 PHENOTYPES

aa

True-breeding

homozygous dominant

parent plant

Aa

Aa

a

a

Aa

Aa

A

AA

Aa

Aa

A

Aa

Aa

Fig. 11-7b1, p.173


Slide40 l.jpg

Punnett Squares of Test Crosses grains, which originate in male floral parts

An F1 plant self-fertilizes

and produces gametes:

F2 PHENOTYPES

Aa

AA

Aa

A

a

AA

Aa

A

Aa

aa

a

Aa

aa

Fig. 11-7b2, p.173


Section 11 3 weblinks and infotrac l.jpg
Section 11.3: Weblinks and InfoTrac grains, which originate in male floral parts

See the latest Weblinks and InfoTrac articles for this chapter online


Dihybrid cross l.jpg
Dihybrid Cross grains, which originate in male floral parts

Experimental cross between individuals that are homozygous for different versions of two traits


Dihybrid cross f 1 results l.jpg
Dihybrid Cross: grains, which originate in male floral parts F1 Results

purple

flowers, tall

white

flowers,

dwarf

TRUE-

BREEDING

PARENTS:

AABB

x

aabb

GAMETES:

AB

AB

ab

ab

AaBb

F1 HYBRID

OFFSPRING:

All purple-flowered, tall


Dihybrid cross f 2 results l.jpg
Dihybrid Cross: grains, which originate in male floral parts F2 Results

X

AaBb

AaBb

1/4 AB

1/4 Ab

1/4 aB

1/4 ab

9/16 purple-flowered, tall

1/4 AB

1/16

AABB

1/16

AABb

1/16

AaBB

1/16

AaBb

3/16 purple-flowered, dwarf

3/16 white-flowered, tall

1/16

AaBb

1/16

AAbb

1/16

Aabb

1/4 Ab

1/16

AABb

1/16 white-flowered, dwarf

1/16

AaBB

1/16

aaBB

1/16

aaBb

1/4 aB

1/16

AaBb

1/16

Aabb

1/16

aaBb

1/16

aabb

1/16

AaBb

1/4 ab


Slide45 l.jpg

AABB grains, which originate in male floral parts

purple-

flowered

tall parent

(homozygous

dominant)

aabb

white-

flowered

dwarf parent

(homozygous

recessive)

X

AB

ab

F1 OUTCOME:

All of the F1 plants are AaBb heterozygotes

(purple flowers, tall stems).

AaBb

Fig. 11-9a, p.175


Slide46 l.jpg

1/4 grains, which originate in male floral parts

1/4

1/4

1/4

meiosis,

gamete

formation

AB

Ab

aB

ab

1/4

1/16

1/16

1/16

1/16

AABB

AABb

AaBB

AaBb

AB

1/4

1/16

1/16

1/16

1/16

Ab

AABb

AAbb

AaBb

Aabb

1/16

1/16

1/16

1/16

AaBB

AaBb

aaBB

aaBb

aB

1/16

1/16

1/16

1/16

1/4

AaBb

Aabb

aaBb

aabb

ab

Fig. 11-9b, p.175


Dihybrid cross f 2 results47 l.jpg
Dihybrid Cross: grains, which originate in male floral parts F2 Results

Dihybrid cross


Independent assortment l.jpg
Independent Assortment grains, which originate in male floral parts

  • Mendel concluded that the two “units” for the first trait were to be assorted into gametes independently of the two “units” for the other trait

  • Members of each pair of homologous chromosomes are sorted into gametes at random during meiosis


Independent assortment49 l.jpg
Independent Assortment grains, which originate in male floral parts

Metaphase I:

OR

A

A

a

a

A

A

a

a

B

B

b

b

b

b

B

B

Metaphase II:

A

A

a

a

A

A

a

a

B

B

b

b

b

b

B

B

Gametes:

B

B

b

b

b

b

B

B

A

A

a

a

A

A

a

a

1/4 AB

1/4 ab

1/4 Ab

1/4 aB


Slide50 l.jpg

Independent Assortment grains, which originate in male floral parts

Nucleus of a

diploid (2n)

reproductive cell

with two pairs of

homologous

chromosomes

Possible alignments

of the two homologous

chromosomes during

metaphase I of meiosis

The resulting alignments

at metaphase II

Allelic combinations

possible in gametes

1/4 AB

1/4 ab

1/4 Ab

1/4 aB

Fig. 11-8, p.174


Tremendous variation l.jpg
Tremendous Variation grains, which originate in male floral parts

Number of genotypes possible in offspring as a result of independent assortment and hybrid crossing is

3n

(n is the number of gene loci at which the parents differ)


Impact of mendel s work l.jpg
Impact of Mendel’s Work grains, which originate in male floral parts

  • Mendel presented his results in 1865

  • Paper received little notice

  • Mendel discontinued his experiments in 1871

  • Paper rediscovered in 1900


Section 11 4 weblinks and infotrac l.jpg
Section 11.4: Weblinks and InfoTrac grains, which originate in male floral parts

See the latest Weblinks and InfoTrac articles for this chapter online


Dominance relations l.jpg
Dominance Relations grains, which originate in male floral parts

Complete dominance

Incomplete dominance

Codominance


Incomplete dominance l.jpg

Incomplete grains, which originate in male floral parts

Dominance

Incomplete Dominance

X

Homozygous

parent

Homozygous

parent

All F1 are

heterozygous

X

F2 shows three phenotypes in 1:2:1 ratio


Abo blood type l.jpg
ABO Blood Type grains, which originate in male floral parts

Codominance: ABO blood types


Slide57 l.jpg

Incomplete Dominance grains, which originate in male floral parts

homozygous parent

X

homozygous parent

All F1 offspring heterozygous for flower color:

Cross two of the F1 plants and the F2 offspring will show three phenotypes in a 1:2:1 ratio:

Fig. 11-11, p.176


Incomplete dominance58 l.jpg
Incomplete Dominance grains, which originate in male floral parts

Incomplete dominance


Codominance abo blood types l.jpg
Codominance: ABO Blood Types grains, which originate in male floral parts

  • Gene that controls ABO type codes for enzyme that dictates structure of a glycolipid on blood cells

  • Two alleles (IA and IB) are codominant when paired

  • Third allele (i) is recessive to others


Slide60 l.jpg

ABO Blood Type grains, which originate in male floral parts

Range of genotypes:

IAIA

IBIB

or

or

IAi

IAIB

IBi

ii

Blood

Types:

A

AB

B

O

Fig. 11-10a, p.176


Slide61 l.jpg

ABO Blood Type grains, which originate in male floral parts

Fig. 11-10b, p.176


Abo and transfusions l.jpg
ABO and Transfusions grains, which originate in male floral parts

  • Recipient’s immune system will attack blood cells that have an unfamiliar glycolipid on surface

  • Type O is universal donor because it has neither type A nor type B glycolipid


Pleiotropy l.jpg
Pleiotropy grains, which originate in male floral parts

  • Alleles at a single locus may have effects on two or more traits

  • Marfan syndrome - Mutation in gene for fibrillin affects skeleton, cardiovascular system, lungs, eyes, and skin


Pleiotropy64 l.jpg
Pleiotropy grains, which originate in male floral parts

Pleiotropic effects of Marfan syndrome


Epistasis l.jpg
Epistasis grains, which originate in male floral parts

  • Interaction between the products of gene pairs

  • Common among genes for hair color in mammals


Epistasis66 l.jpg
Epistasis grains, which originate in male floral parts

Fig. 11-13, p.177


Coat color in retrievers l.jpg
Coat Color in grains, which originate in male floral parts Retrievers

BBEE

X

bbee

F1puppies

are all BbEe

F2puppies

BE

Be

bE

be

BE

black

BBEE

BBEe

BbEE

BbEe

Be

BBee

BbEe

Bbee

BBEe

brown

bE

BbEe

bbEE

bbEe

BbEE

yellow

be

Bbee

bbEe

bbee

BbEe


Coat color in retrievers68 l.jpg
Coat Color in Retrievers grains, which originate in male floral parts

Coat color in Labrador retrievers


Comb shape in poultry l.jpg
Comb Shape in Poultry grains, which originate in male floral parts

RRpp

(rose comb)

rrPP

(pea comb)

P:

X

RrPp (all walnut comb)

F1:

F2:

9/16 walnut

3/16 rose

3/16 pea

1/16 single

rrpp

rrPP

rrPp

RRpp

Rrpp

RRPP

RRPp

RrPP

RrPp


Slide70 l.jpg

Comb Shape in Poultry grains, which originate in male floral parts

rose comb

pea comb

walnut comb

single comb

X

rose

RRpp

pea

rrPP

F1

all walnut

RrPp

RrPp

RrPp

F2

9/16 walnut

RRPP, RRPp,RrPP, or RrPp

3/16 rose

RRpp or Rrpp

3/16 pea

rrPP or rrPp

1/16 single

rrpp

Fig. 11-12, p.177


Comb shape in poultry71 l.jpg
Comb Shape in Poultry grains, which originate in male floral parts

Comb shape in chickens


Coat color l.jpg
Coat Color grains, which originate in male floral parts

Coat color in the Himalayan rabbit


Slide73 l.jpg

Fig. 11-14, p.177 grains, which originate in male floral parts


Section 11 5 weblinks and infotrac l.jpg
Section 11.5: Weblinks and InfoTrac grains, which originate in male floral parts

See the latest Weblinks and InfoTrac articles for this chapter online


Crossing over l.jpg
Crossing Over grains, which originate in male floral parts

  • Each chromosome becomes zippered to its homologue

  • All four chromatids are closely aligned

  • Nonsister chromosomes exchange segments


Effect of crossing over l.jpg
Effect of Crossing Over grains, which originate in male floral parts

  • After crossing over, each chromosome contains both maternal and paternal segments

  • Creates new allele combinations in offspring


Linkage groups l.jpg
Linkage Groups grains, which originate in male floral parts

  • Genes on one type of chromosome

  • Fruit flies

    • 4 homologous chromosomes

    • 4 linkage groups

  • Not all genes on chromosome are tightly linked


Full linkage l.jpg

A grains, which originate in male floral parts

A

a

B

B

b

A

a

B

b

a

b

Full Linkage

x

Parents:

AB

ab

F1 offspring:

All AaBb

meiosis, gamete formation

Equal ratios of two types of gametes:

Figure 11.15Page 178

50% AB

50% ab


Incomplete linkage l.jpg

A grains, which originate in male floral parts

a

a

c

c

C

A

C

Incomplete Linkage

AC

ac

x

Parents:

F1 offspring:

All AaCc

meiosis, gamete formation

a

a

A

A

Unequal ratios of four types of gametes:

C

c

C

c

parental

genotypes

recombinant

genotypes

Figure 11.15Page 178


Crossover frequency l.jpg
Crossover Frequency grains, which originate in male floral parts

Proportional to the distance that separates genes

A

B

C

D

Crossing over will disrupt linkage between A and B more often than C and D

In-text figurePage 178


Linkage mapping in humans l.jpg
Linkage Mapping in Humans grains, which originate in male floral parts

  • Linkage maps based on pedigree analysis through generations

  • Color blindness and hemophilia are very closely linked on X chromosome


Crossing over82 l.jpg
Crossing Over grains, which originate in male floral parts

Crossover review


Section 11 6 weblinks and infotrac l.jpg
Section 11.6: Weblinks and InfoTrac grains, which originate in male floral parts

See the latest Weblinks and InfoTrac articles for this chapter online


Videos cnn84 l.jpg
Videos: CNN grains, which originate in male floral parts

Ask your Thomson Sales Representative for these volumes on CD or VHS

  • Anatomy and Physiology, 2002, Vol. 6,Trigger for Parkinson’s (2:44)


Environmental effects on plant phenotype l.jpg
Environmental Effects on Plant Phenotype grains, which originate in male floral parts

  • Hydrangea macrophylla

  • Action of gene responsible for floral color is influenced by soil acidity

  • Flower color ranges from pink to blue


Slide86 l.jpg

Environmental Effects on Plant Phenotype grains, which originate in male floral parts

Fig. 11-17a, p.179


Slide87 l.jpg

Environmental Effects on Plant Phenotype grains, which originate in male floral parts

Fig. 11-17b, p.179


Temperature effects on phenotype l.jpg
Temperature Effects grains, which originate in male floral parts on Phenotype

  • Rabbit is homozygous for an allele that specifies a heat-sensitive version of an enzyme in melanin-producing pathway

  • Melanin is produced in cooler areas of body

Figure 11.16Page 179


Slide89 l.jpg

Fig. 11-16, p.179 grains, which originate in male floral parts


Section 11 7 weblinks and infotrac l.jpg
Section 11.7: Weblinks and InfoTrac grains, which originate in male floral parts

See the latest Weblinks and InfoTrac articles for this chapter online


Campodactyly unexpected phenotypes l.jpg
Campodactyly: grains, which originate in male floral parts Unexpected Phenotypes

  • Effect of allele varies:

    • Bent fingers on both hands

    • Bent fingers on one hand

    • No effect

  • Many factors affect gene expression


Continuous variation l.jpg
Continuous Variation grains, which originate in male floral parts

  • A more or less continuous range of small differences in a given trait among individuals

  • The greater the number of genes and environmental factors that affect a trait, the more continuous the variation in versions of that trait


Human variation l.jpg
Human Variation grains, which originate in male floral parts

  • Some human traits occur as a few discrete types

    • Attached or detached earlobes

    • Many genetic disorders

  • Other traits show continuous variation

    • Height

    • Weight

    • Eye color


Slide94 l.jpg

Continuous Variation grains, which originate in male floral parts

  • Variation in human eye color

Fig. 11-18, p.180


Describing continuous variation l.jpg

(line of bell-shaped curve indicates continuous variation in population)

Number of individuals with

some value of the trait

Number of individuals with

some value of the trait

Range of values for the trait

Range of values for the trait

Describing Continuous Variation


Slide96 l.jpg

Describing Continuous Variation population)

The line of a bell-shaped curve reveals

continuous variation in the population

Number of individuals with

some value of the trait

Range of values for the trait

Fig. 11-19a, p.180


Slide97 l.jpg

Describing Continuous Variation population)

Number of individuals with

some value of the trait

Range of values for the trait

Fig. 11-19b, p.180


Slide98 l.jpg

Describing Continuous Variation population)

Fig. 11-20, p.181


Continuous variation99 l.jpg
Continuous Variation population)

Continuous variation in height


Slide100 l.jpg

A population)

a

AA (dominant)

A

AA

Aa

Aa (dominant)

The expected

phenotypic

ratio of 3:1

Aa (dominant)

a

Aa

aa

aa (recessive)

p.182


Slide101 l.jpg

Fig. 11-21, p.183 population)


Slide102 l.jpg

dominant population)

recessive

Fig. 11-22, p.183


Slide103 l.jpg

dominant population)

recessive

Fig. 11-22, p.183


Slide104 l.jpg

Fig. 11-23, p.184 population)


Slide105 l.jpg

Fig. 11-24, p.185 population)