Drug classification
Download
1 / 20

drug classification - PowerPoint PPT Presentation


  • 673 Views
  • Updated On :

Drug Classification. Lesson 1. Psychopharmacology. Study of drugs that affect nervous system Study effects of the drug e.g. prenatal methamphetamine Drugs as tools to study functions of nervous system e.g., cocaine & reward systems ~. My Interests. Prenatal & postnatal consequenses

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about 'drug classification' - Olivia


An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript

Psychopharmacology l.jpg
Psychopharmacology

  • Study of drugs that affect nervous system

  • Study effects of the drug

    • e.g. prenatal methamphetamine

  • Drugs as tools to study functions of nervous system

    • e.g., cocaine & reward systems ~


My interests l.jpg
My Interests

  • Prenatal & postnatal consequenses

    • Drugs of abuse

    • Environmental teratogens

  • Prenatal

    • effects on neural development

    • Postnatal behavior

  • Postnatal

    • Addiction ~


Drug effects are variable l.jpg
Drug effects are variable!

  • Course Goal: Understanding factors that produce variability

    • Pharmacological

    • Neurophysiological

    • Psychological

    • Survey of specific drugs ~


Psychoactive drugs l.jpg
Psychoactive Drugs

  • Drug

    • Biologically Active

    • chemically alters cell structure/function

    • Exclude: Natural Foods/Water

  • Alters function of nervous system

    • Consciousness

    • Emotions

    • Perceptions

    • Behavior ~


Drug names l.jpg
Drug Names

  • At least 3 names

  • Chemical name

    • describes molecular structure

  • Generic name

    • official legal name

  • Trade name

    • brand name

  • Street name ~


Example amphetamine l.jpg

dl-2 amino-1 phenylpropane

dl-amphetamine

Benzedrine

speed, bennies, whites, etc.~

chemical

generic

trade

street

Example: Amphetamine


Example valium l.jpg

7-chloro--1-methyl-5-phenyl-3H-1,4-benzodiazepin-2[1H]-one

diazepam

valium

tranks, downers, blues, yellows

chemical

generic

trade

street

Example: Valium


Example lunesta l.jpg

(+)-(5S)-6-(chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b] pyrazin-5-yl 4-methylpiperazine-1-carboxylate

eszopiclone

Lunesta

?

street

Example: Lunesta

  • chemical

  • generic

  • trade


Drug equivalence l.jpg
Drug Equivalence pyrazin-5-yl 4-methylpiperazine-1-carboxylate

  • Important to know when prescribing

  • Chemical equivalence

    • identical chemical compounds

    • e.g., Miltown & Equanil (meprobamate)

  • Biological equivalence

    • different chemical compounds

    • affect the same systems in same way

    • e.g., Prozac vs. Zoloft ~


Drug equivalence11 l.jpg
Drug Equivalence pyrazin-5-yl 4-methylpiperazine-1-carboxylate

  • Clinical equivalence

    • same behavioral effect

    • different chemical compounds affecting different systems

    • e.g., thorazine vs. lithium ~


Drug classification12 l.jpg
Drug Classification pyrazin-5-yl 4-methylpiperazine-1-carboxylate

  • Several schemes

    • use depends on goals

  • Not easy to classify

    • each drug wide range of properties

  • Psychopharmacology:

    • CNS & Behavioral ~


Text cns behavioral effects l.jpg
Text: CNS & Behavioral Effects pyrazin-5-yl 4-methylpiperazine-1-carboxylate

  • CNS Stimulants

    • Cocaine, amphetamine

  • CNS Depressants

    • Barbiturates, alcohol

  • Analgesics

    • Morphine, codeine

  • Hallucinogens

    • Mescaline, LSD, psilocybin

  • Psychotherapeutics

    • Prozac, thorazine ~


Drug laws legal classification l.jpg
Drug laws & legal classification pyrazin-5-yl 4-methylpiperazine-1-carboxylate

  • Controlled Substances Act of 1970

  • 5 schedules

    • abuse potential

    • medicinal value

  • Schedule I

    • high abuse potential

    • no accepted medicinal value ~


Drug laws legal classification15 l.jpg
Drug laws & legal classification pyrazin-5-yl 4-methylpiperazine-1-carboxylate

  • Schedule II

    • high abuse potential

    • accepted medicinal value

  • Schedule III

    • moderate abuse potential

  • Schedule IV - low abuse potential

  • Schedule V - abuse potential < IV ~


Drug schedules regulation l.jpg
Drug Schedules & Regulation pyrazin-5-yl 4-methylpiperazine-1-carboxylate

  • Schedule I

    • Cannot be prescribed

    • Research: tightly regulated

  • Schedule II

    • Can prescribe, but no refills

    • Research: yearly registration

  • Schedule III, IV, V

    • Prescribe up to 5 refills over 6 months ~


Classification problems l.jpg
Classification Problems pyrazin-5-yl 4-methylpiperazine-1-carboxylate

  • Alcohol effects

    • General nervous system depressant

  • Effects depend on dose

    • Low dose  behavioral excitation

    • High dose  behavioral inhibition

  • What are the effects of alcohol?

    It depends! ~


Another example l.jpg
Another Example pyrazin-5-yl 4-methylpiperazine-1-carboxylate

  • Attention Deficit Hyperactive Disorder

    • hyperkinesis

  • Treatment: Ritalin

    • Methylphenidate

  • classified as a sedative?

  • No, a stimulant ~


  • No magic bullets l.jpg
    No Magic Bullets! pyrazin-5-yl 4-methylpiperazine-1-carboxylate

    • Drug delivered into system

      • Affects all cells that have receptors

    • Desired effect

      = therapeutic effect

    • All other effects

      = side effects

    • All drugs have multiple effects ~


    What are a drug s effects l.jpg
    What are a drug’s effects? pyrazin-5-yl 4-methylpiperazine-1-carboxylate

    • IT DEPENDS

      • Many sources of variability

      • A focus of this course

    • Deciding to use a drug

      • weigh benefits vs. risks

      • there are always risks ~


    ad