Lung F unction T esting in School-Age Children. Paul Aurora Great Ormond Street Hospital for Children, & Institute of Child Health, London. Structure of talk. Why bother? What do we need from a lung function test? What tests are available? Spirometry Other tests. Why bother?.
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Great Ormond Street Hospital for Children,
& Institute of Child Health,
Average reduction of
22 % in FEV0.5 in infants
with CF vs healthy infants
after adjustment for body size,
age, sex etc
Ranganathan et al
Between occasion repeatability controls
Between occasion repeatability
Chan E, Thorax. 2003 Apr;58(4):344-7.
Accurate anthropometry essential for controls
meaningful interpretation of results
How often do you calibrate your stadiometer?
Expired Vital Capacity (%)
NEP Equipment for assessing flow controls
limitation during RVRTC
Jones et al 2000
NEP to assess flow limitation controls
- Jones et al AJRCCM 2000
No Flow limitation
Spirometry in infants controls
A = Wash-in phase controls
B = Disconnection
C = Washout
(Zrs, = Prs/ V’rs)
Forced Oscillation controls
‘head’ generator to minimize upper airway artefact