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Human Molecular Genetics Section 14–3 . This section explains how genetic engineering techniques are being used to study the genes and chromosomes in the human genome. It also describes how this information is used for gene therapy. Human DNA Analysis .

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Human molecular genetics section 14 3

Human Molecular Genetics Section 14–3

This section explains how genetic engineering techniques are being used to study the genes and chromosomes in the human genome. It also describeshow this information is used for gene therapy.


Human dna analysis
Human DNA Analysis

Biologists search the volumes of the human genome using ______ .

  • sequences of DNA bases


Human dna analysis1
Human DNA Analysis

Why might prospective parents decide to have genetic testing?

Genetic tests can determine whether prospective parents risk passing alleles for genetic disorders to their children.


Human dna analysis2
Human DNA Analysis

Circle the letter of each sentence that is true about genetic testing.

  • Labeled DNA probes can be used to detect specific sequences found in disease causing alleles.

  • Some genetic tests use changes in restriction enzyme cutting sites to identify disease causing alleles.

  • DNA testing makes it possible to develop more effective therapy and treatment for individuals affected by genetic disease.


Dna fingerprinting
DNA FINGERPRINTING

What is DNA fingerprinting?

  • It is the identification of individuals by a method that analyzes sections of DNA that have little or no known function but vary widely from one individual to another.


Dna fingerprinting1
DNA FINGERPRINTING

Circle the letter of each source for a DNA sample from an individual.

  • a. blood

  • b. sperm

  • d. hair with tissue at the base


Dna fingerprinting2
DNA FINGERPRINTING

Is the following sentence true or false?

  • DNA evidence is not reliable enough to be used to convict criminals.

  • FALSE


The human genome project
The Human Genome Project

What is the Human Genome Project?

  • It is an ongoing effort to analyze the human DNA sequence.


Human genome project
Human Genome Project

Circle the letter of each sentence that is true about the Human Genome Project.

Researchers completed the genomes of yeast and fruit flies during the same timethey sequenced the human genome.

A working copy of the human genome was completed in June 2000.


Human genome project1
Human Genome Project

What were the three major steps in the process of sequencing the human genome?

  • Widely separated regions of DNA on each chromosome were sequenced.

  • Random fragments of DNA were sequenced.

  • Computers found overlapping regions between the fragments and positioned them relative to the known markers.


Human genome project2
Human Genome Project

What is an open reading frame, and what is it used for?

  • It is a series of DNA bases that will produce an mRNA sequence. Scientists use it to locate genes.


Human genome project3
Human Genome Project

The mRNA coding regions of most genes are interrupted by Introns.


Human genome project4
Human Genome Project

List three other parts of the gene that researchers look for.

  • Promoter

  • “Start” site for transcription

  • “Stop” site for transcription


Human genome project5
Human Genome Project

Why are biotechnology companies interested in genetic information?

  • They are trying to use this information to develop new drugs and treatments for diseases.


Human genome project6
Human Genome Project

Is the following sentence true or false?

Human genome data is top secret and can be accessed only by certain people.

  • False


Gene therapy
Gene Therapy

What is gene therapy?

  • In gene therapy, an absent or faulty gene is replaced by a normal, working gene.


Gene therapy1
Gene Therapy

Circle the letter of each sentence that is true about gene therapy.

  • When the normal copy of the gene is inserted, the body can make the correct protein, which eliminates the disorder.

  • Viruses are often used to carry the normal genes into cells.


Gene therapy2
Gene Therapy

Have all gene therapy experiments been successful?

  • No

  • attempts to treat cystic fibrosis by spraying genetically engineered viruses into breathing passages have not produced alasting cure.


Gene therapy ethics
Gene Therapy Ethics

Ethical Issues in Human Genetics

What other changes could be made to the human genome by manipulating humancells?

  • Biologists could try to engineer taller people or change eye color, hair texture, sex, blood group, or appearance. They could even clone human beings.


Gene therapy ethics1
Gene Therapy Ethics

What is the goal of biology?

  • It is to gain a better understanding of the nature of life.


Gene therapy ethics2
Gene Therapy Ethics

What is the responsibility of society in biology?

  • Society will have to learn to use wisely the tools that science has given it. It will have to develop an ethical consensus of what should and should not be done with the human genome.


Gene therapy ethics3
Gene Therapy Ethics

Is the following true or false?

  • Scientists should be expected to make all ethical decisions regarding advances in human genetics.

  • false


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