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Hippuric Acid - A uremic toxin

Compounds which are retained in the blood during kidney failure<br>Interact negatively with the normal biological functions of the body<br>Hippuric Acid is an example of one such toxin<br>

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Hippuric Acid - A uremic toxin

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  1. Hippuric Acid - A uremic toxin By Pharmaffiliates

  2. What are Uremic toxins • Compounds which are retained in the blood during kidney failure • Interact negatively with the normal biological functions of the body • Hippuric Acid is an example of one such toxin

  3. What is Hippuric Acid • A normal component of urine • Typically increased with increased consumption of phenolic compounds • Chemically, a glycine conjugate of benzoate • A uremic toxin, at the time of kidney failure • Formed from aromatic amino acids by gastrointestinal flora • Or taken directly as preservatives from food and beverages

  4. Importance of Hippuric acid • Used as a biomarker to study  • cell biology • chemical biology • bioactive small molecules • amino acid derivatives • peptide synthesis • chemical synthesis and nutrition.  • Used to inform the metabolism and urinary excretion of procyanidins.

  5. Pharmaffiliates-manufacturer and supplier of Hippuric acid and its Impurities • Pharmaffiliates identified, isolated, purified and characterized 3 impurities of Hippuric acid 1. 2-Chloro Hippuric Acid 2. 3-Chloro Hippuric Acid 3. 4-Chloro Hippuric Acid • Available in pack sizes of 25mg and 50mg vials • Customized pack sizes available • Stable isotope of Hippuric acid is also available in pack sizes of 1mg and 10mg • Each Certified standard is shipped with a Certificate of Analysis, MSDS and all the required documentation • COA meets all the regulatory requirements

  6. About Pharmaffiliates • A research driven integrated Contract Research Organization • Specializes in custom synthesis of Pharmaceutical impurities, metabolites, intermediates, glucuronides and stable isotopes • An eminent name worldwide, as a leading manufacturer and supplier of reference material • Successfully passed major second and third party audits which include NABL accreditation, ISO Guide 34 and USFDA.

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