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Concentrated extract of bioactive peptides and natural prebiotics

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Nutrigenomics

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Nutrigenomics

PROTIBIA C-90

Nutritional Supplement

Provides natural ingredients

and nutritional solutions for

animal welfare.


Nutrigenomics

Bioala S.A

Studies developed on bioactive peptides derived from animal sources like milk, eggs, fishes. As well as plant sources such as soybeans, chickpeas, sunflower, rapeseed, lupine, and others.

Within its bioactivity, the peptides could alter cell metabolism and work like hormones or neurotransmitters playing an important physiological role through hormone-receptor interactions and signaling cascades; also can make actions on the metabolism regulation (water, minerals and other nutrients) controlling excretory glands, adjusting blood pressure, improving the growth of the individual, sexual behavior, appetite and the effects of stress paths on the central nervous

The functions of bioactive peptides as antihypertensive agents, antioxidants, antimicrobials, naming a few, allow their use as ingredients in the development of functional foods and thus obtain a beneficial effect for some functions of animal body, to produce an improvement in their health or reducing risk of disease.


Nutrigenomics

Bovines, porks, poultries, fishes, crustaceans, frogs, horses

Technologic Proposal

Improver of nutritional value

Peptides & Proteins

Bioactive Peptides

Improver nutritional value

Antioxidant

+

Peptides (hydrolisates)

SOURCE: Plant Seeds

Fish, cephalopods

Natural antioxidantsSOURCE: Red Wine                 Grapeseed

Aplication


Nutrigenomics

BIOACTIVE PEPTIDES:NEW HEALTH PROMOTERS

  • Bioala S.A.: Has developed specific fragments of a protein diet that in addition to their nutritional value have biological activity and the capacity to regulate physiological processes.

  • Protibia C-90: These are peptides that constitute a large number of specific biological messengers. The sequences defined of amino acids that are inactive within the protein of origin, have special properties once they are released by enzyme action.Their physiological function can be exercised by its absorptive capacity at the intestine, and transported by blood circulation, or locally in the gastrointestinal tract. In the latter case, is not necessary to be absorbed for to assume functional action, but they must resist the digestive enzymes a necessary time.

Currently Foods are being considered not only as a nutrients source for maintenance and body growth but also as an important resource for physiologically active compounds known as nutraceuticals.

This trend in eating patterns has generated a new development in the food and nutrition science area of multidisciplinary nature.

PROTIBIA C-90


Nutrigenomics

Biological activity of bioactive peptides

Many biologically active compounds came from marine organisms. Because they live in a more competitive and aggressive environment compared to terrestrial organisms, they need to produce molecules with potent biological activity to survive.

Production methods of Bioactive Peptides :

Bioactive peptides obtained by enzymatic hydrolysis are more appropriate for the pharmaceutical and food industry, because they contain low levels of wastes such as organic solvents or toxic chemicals

  • Solvent extraction

  • Microbial fermentation

  • Enzymatic hydrolysis

  • Bioala Extraction Process (patent pending)


Nutrigenomics

Polyphenols Technology

POLYPHENOLS

Seed

Wine

Chilean Technology


Nutrigenomics

Grape Polyphenols

Natural Antioxidant

POLYPHENOLS ACTIVES

Polyphenols are potent antioxidants

They are groups of compounds, present

in the nature and, therefore, in the diet.

Its chemical structure makes thempowerful antioxidants.

Give up electrons

Capacity

Reaction

Red Wine and Grape Seed.CHILE has large quantitiesand better quality of Polyphenolsthrough the Wine Industry.

Source of Polyphenols

Fuente: (PROPIEDADES ANTIOXIDANTES DEL VINO Y SUS COMPONENTES Federico Leighton , PUCC, 1997)

http://www.bio.puc.cl/vinsalud/publica.htm


Nutrigenomics

ActionMechanism

¿How Polyphenols act?

Polyphenols defends cells through control the free radicals

INSIDE THE CELL: When

nutrients are metabolized to generate

energy.

ENVIRONMENT: Pollution and Chemicals.

¿What are Free Radicals?

  • The free radical is an oxygen atom with seven electronsThe stable oxygen atom has 8 electrons.Becomes unstable when it loses an electron.

Oxigen Atom

ASKS BORROW ONE ELECTRONS TO THE CELL MEMBRANE


Nutrigenomics

Action Mechanism

For to avoids oxidation, the Polyphenols give electrons

to low density lipoproteins (LDL), which are located

inside the cells and the cell membrane.

By the action of free radicals, the cell membrane is damaged, and this accelerates their aging and other diseases.

Oxigen Atom


Nutrigenomics

Pedicel

Pulp

Brush

Skyn

Hydroxybenzoic

Acids

Seed

Anthocyanins

Tannins

Flavonols

Tannins or procyanidins

Tannins or procyanidins

Wine Extract and Health

Cross section of grapes

Free Radicals

Antioxidants

Disease

Health

Antioxidants

Parts of the grape


Nutrigenomics

NutritionalScheme

Breeder Nutrition

Peptide of new generation

from vegetables and marine animals.

Highly concentrated Polyphenols from chilean red wines.

FEED(Nutrients)

+

PROTIBIA C-90

GROWTHDEFENSES

DIGESTION PROCESSES

(Feces / Urine / Gases)

INCREASE

PROTIBIA C-90

CONCENTRATED EXTRACT OF BIOACTIVE PEPTIDES AND NATURAL PREBIOTICS

ENERGY

STRUCTURAL AMINOACIDS

METABOLIC PROCESSES


Nutrigenomics

Food and Nutrition

FEEDING

Voluntary Act

NUTRITION

Involuntary Act


Nutrigenomics

Digestive metabolic process of the traditional animal nutrition


Nutrigenomics

Digestive metabolic process of animal nutrition withPROTIBIA C-90

TheProtibia C-90, improves the digestibility of nutrients in the 1st Stage.


Nutrigenomics

What guarantee us

Digestibility analysis


Nutrigenomics

What guarantee us

Peptide Analysis


Nutrigenomics

What guarantee us

PAC Verification


Nutrigenomics

PROTIBIA C-90

Concentrated extract of bioactive peptides and natural prebiotics

Properties

  • High content of metabolizable protein, favoring the feed conversion

  • Benefits the metabolism and animal wellness

  • High digestibility and nutrient absorption:

  • * Low molecular weight peptides

  • * Low anti-nutritional factors

  • * Specific enzymes by size of protein substrate

  • Improved the performance of growth:

  • * Specific amino acid profile* Reduced incidence of diarrhea

  • Very stable product that guarantees a long and healthy life of young animals.


Nutrigenomics

Product Information

Product for exclusive use in animal feed


Nutrigenomics

Extracto de vino y Salud

Extracto de vino y Salud

Process


Nutrigenomics

Presentation


Nutrigenomics

Extracto de vino y Salud

Nutrigenomics

Where are we gonig with nutrition

Communitary Nutrition

  • DNA databases of nutrients

  • Molecular epidermiology

  • Biotechnological foods

  • Primary prevention feeding

  • Food – drug complex

Knowledge

Personalized

Nutrition

Emerging ScienceNew channels of informationUsers with more information

  • Molecular Nutrition

  • Biomarkers

  • Personal test kits

  • Internet Dietician

FunctionalFoods

  • Nutri-pharmacology

  • Bioanalytic profile

  • Health claims

General

Diet

Information

  • Geographical epidemiology

  • Identify and document

YESTERDAY

TODAY

TOMORROW


Nutrigenomics

Extracto de vino y Salud

www.bioala.com

info@bioala.com

Philippi 325, Valparaíso


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