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angina pectoris

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Angina pectoris - Nitrates. NitroglycerinOrganic nitrateActs on vascular smooth muscle to promote vasodilationPrimarily works on veins, only modest dilation of arteriolesDecreases oxygen demand by decreasing venous return => use in stable anginaIt was originally believed that nitrates and nitrites dilated coronary blood vessels, thereby increasing blood flow to the heart. It is now believed that atherosclerosis limits coronary dilation and that the benefits of nitrates and nitrites are due1140

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