Altered Hematologic Function: Erythrocytes. Physical Characteristics of Blood. Heavier, thicker, and 3-4 X more viscous than water 38 o C (100.4 o F) pH : 7.35 – 7.45 4-6 liters in an adult Varies with electrolyte concentration and amount of adipose tissue. Blood Volume.
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Altered Hematologic Function:Erythrocytes
Erythrocytes – red blood cells- RBC’s
Leukocytes – white blood cells – WBC’s
Thrombocytes – platelets – cell fragments
Pernicious Anemia is also associated with:
Heavy alcohol consumption
Other autoimmune conditions
Complete or partial removal of the stomach can cause intrinsic factor deficiency
Thalassemia major is an inherited form of hemolytic anemia, characterized by red blood cell (hemoglobin) production abnormalities. This is the most severe form of anemia, and the oxygen depletion in the body becomes apparent within the first 6 months of life. If left untreated, death usually results within a few years. Note the small, pale (hypochromic), abnormally-shaped red blood cells associated with thalassemia major.