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Lecture 25 Respiration #2PowerPoint Presentation

Lecture 25 Respiration #2

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### Lecture 25Respiration #2

Measurement of airway resistance

- Dubois shutter method
- Measurement of pressure in full body plethysmograph using calibration Pump
- PV=NRT = gas law

Retrograde catheter(set R=0)

Pressure units

- Atmospheric pressure ~14.7 pounds/sq inch
- Daily barometric pressure - 30 cm Hg or 762 mmHg
- Or 10.3 meters water or 33 ft

Pressure calculations

- Today’s barometric pressure = 30.03 cm Hg
- Or 760 mmHg
- % Oxygen = 20.94%
- Partial pressure of oxygen ~160 mmHg
- Pressure of oxygen in hemoglobin = 100
- Venous oxygen pressure = 40

Hemoglobin dissociation curve

Effect pf Ph (Push to Right)

Effect of sickle cell (push to left)

Carbon monoxide

Temperature (push to right)

Organic Phosphates (push to right)

Other pressure effects

- High altitude
- Mount Kilimanjaro
- Mount Everest
- Blood Oxygen saturation – ear clip
- Measurement of PO2
- Carbon dioxide in brain – hyper ventilation
- Sleep patterns
- Artificial lungs

Ventilators

- Design
- Purpose
- How it feels
- High frequency type
- Neonatal nursery
- Danger of pure oxygen

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