An Experimental Paradigm for Developing Adaptive Treatment Strategies. S.A. Murphy NIDA Meeting on Treatment and Recovery Processes January, 2004. Setting : Management of chronic, relapsing disorders such as alcohol addiction, substance abuse and mental illness Characteristics:
Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.
An Experimental Paradigm for Developing Adaptive Treatment Strategies
NIDA Meeting on Treatment and Recovery Processes
GOAL: Provide experimental paradigm for developing treatment decision rules.
EXAMPLE: Treatment of alcohol dependency. Primary outcome is a summary of heavy drinking scores over time
GOAL: Design trials that have the goal of developing treatment decision rules leading to a minimization of the mean response, (mean drinking score over time).
PROPOSAL: Sequential within-person randomization: Randomize at each decision point.
The paper can be found at