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mutS homolog 6

https://www.creativebiomart.net/symbolsearch_MSH6.htm<br>MSH6 is a mismatch repair gene which is deficient in a high proportion of patients with microsatellite instability (MSI-H). This finding is associated with the autosomal dominant condition known as Hereditary Non-Polyposis Colon Cancer (HNPCC). The anti-MmutS homolog 6

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mutS homolog 6

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  1. MSH6 https://www.creativebiomart.net/symbolsearch_ MSH6.htm mutS homolog 6 BackgroundMSH6 is a mismatch repair gene which is deficient in a high proportion of patients with microsatellite instability (MSI-H). This finding is associated with the autosomal dominant condition known as Hereditary Non-Polyposis Colon Cancer (HNPCC). The anti-M SynonymsMSH6; mutS homolog 6 (E. coli); GTBP, mutS (E. coli) homolog 6; DNA mismatch repair protein Msh6; p160; GTMBP; hMSH6; sperm-associated protein; mutS-alpha 160 kDa subunit; G/T mismatch-binding protein; GTBP; HSAP; HNPCC5 Recombinant Proteins Cell & Tissue Lysates Cat.# Product name Source (Host) Species MSH6-2412H Recombinant Human MSH6, GST-tagged E. coli Human GST +Inquiry MSH6-2413H Recombinant Human MSH6, His-tagged His +Inquiry MSH6-2414H Recombinant Human MSH6, GST-tagged Wheat germ Human GST +Inquiry MSH6-10134M Recombinant Mouse MSH6 ProteinMammalian Cells His +Inquiry MSH6-2873R Recombinant Rhesus monkey MSH6 Protein, His-tagged Mammalian Cells Rhesus Macaque MSH6-9649Z Recombinant Zebrafish MSH6 Mammalian Cells His +Inquiry Involved Pathway MSH6 involved in several pathways and played different roles in them. We selected most pathways MSH6 participated on our site, such as Mismatch repair, Pathways in cancer, Colorectal cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with MSH6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site. Pathway NamePathway Related Protein Mismatch repairRPA2; PMS2; RPA1; RFC1; MLH1; MSH2; POLD2; MLH3; PCNA; RFC4 Pathways in cancerCCNE1; RAD51; FZD8; HGF; PLEKHG5; RALBP1; CDC42; BRCA2; PTGER2; FZD1 Colorectal cancerTRP53; CASP9; RAC3; PIK3CB; CYCS; MAPK1; MAPK8; MSH6; PIK3CD; PIK3R3 TagPrice E. coli Human Mouse His +Inquiry Zebrafish

  2. Protein Function MSH6 has several biochemical functions, for example, contributes_to ADP binding, contributes_to ATP binding, contributes_to ATPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MSH6 itself. We selected most functions MSH6 had, and list some proteins which have the same functions with MSH6. You can find most of the proteins on our site. FunctionRelated Protein Function contributes_to ADP bindingRelated Protein MSH6; ATP5D; MSH2 Function contributes_to ATP bindingRelated Protein MSH2; ABCG8; ATP5D; SFRP5; ATP1B1; MSH6; ATP1A2 Function contributes_to ATPase activityRelated Protein ATP5B; ATP5L; ATP1B1; SFRP5; ATP6V1H; PPP2R4; ATP5E; ATP5H; RUVBL2; MSH6 Function DNA-dependent ATPase activityRelated Protein ERCC2; MSH2; RAD51L3; DMC1; CHD8; CHD6; MSH5; ERCC6; MSH3; RAD51D Function contributes_to MutLalpha complex bindingRelated Protein MSH2; MSH6 Function chromatin bindingRelated Protein PRKCBB; DMRT1; HMGB4; SIRT7; PATZ1; LEF1; SSBP1; ORC1L; PAX3; GATA4 Function contributes_to double-stranded DNA bindingRelated Protein MSH2; STRA13; MSH6; APITD1 Function contributes_to four-way junction DNA bindingRelated Protein XRCC3; MSH6; RAD51L1; RAD51L3; RAD51B; XRCC2; MSH2; RAD51C; RAD51D Function contributes_to guanine/thymine mispair bindingRelated Protein MSH6; MSH2 Function contributes_to magnesium ion bindingRelated Protein MSH2; MSH6 Function methylated histone bindingRelated Protein MSH6; CBX4; MSL3; L3MBTL2; JHDM1D; RRP8; CAPNS2; PHF1; PHF19; SUZ12 Function mismatched DNA bindingRelated Protein MSH4; MLH3; PMS1; MSH6; MSH5; TDG; MLH1 Function contributes_to mismatched DNA bindingRelated Protein MSH6; MSH3; MSH2 Function contributes_to oxidized purine DNA bindingRelated Protein MSH6; MSH2 Function protein bindingRelated Protein TBX5A; PYDC1; DIABLO; HDHD2; UBE2U; RICTOR; LPHN1; IL36RN; RASAL2; NFKB2 Function contributes_to protein bindingRelated Protein MEF2A; POLR2A; TAF10; MLH1; CPSF3L; INTS10; INHA; MSH2; PAK1; ACVR2A Function NOT protein homodimerization activityRelated Protein MSH6; NUDT16L1; DDIT3; MYO9B; EXT2; MSH3; KCNA3; MLXIPL; MECOM Function contributes_to single guanine insertion bindingRelated Protein MSH6; MSH3; MSH2 Function contributes_to single thymine insertion bindingRelated Protein MSH2; MSH6

  3. Interacting Protein MSH6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MSH6 here. Most of them are supplied by our site. Hope this information will be useful for your research of MSH6. MSH2; MYC; 41_bp_heteroduplex; BRCA1; MCC; CASP4; PSMD4; HRAS; MAP2K1; q5ngv3_fratt; NANS; midostaurin

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