eukaryotic translation initiation factor 5

1. EIF5 eukaryotic translation initiation factor 5 BackgroundEukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of;bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex. The resulting;functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations (summary by Si;et al., 1996 (PubMed 8663286)). SynonymsEIF5; eukaryotic translation initiation factor 5; eIF-5; EIF-5A Recombinant Proteins Cell & Tissue Lysates Cat.#Product name Source (Host) SpeciesTag Price EIF5-478HRecombinant Human EIF5 Protein (1-431 aa), His-SUMO-taggedE. coliHuman His-SUMO +Inquiry EIF5-27177THRecombinant Human EIF5 protein, GST-tagged Wheat GermHuman GST+Inquiry EIF5-8633HRecombinant Human EIF5, GST taggedE. coli Human GST+Inquiry EIF5-2069RRecombinant Rat EIF5 Protein Mammalian Cells Rat His+Inquiry EIF5-1627CRecombinant Chicken EIF5 Mammalian Cells

2. ChickenHis+Inquiry EIF5-9994ZRecombinant Zebrafish EIF5Mammalian Cells ZebrafishHis+Inquiry Involved Pathway EIF5 involved in several pathways and played different roles in them. We selected most pathways EIF5 participated on our site, such as Cap-dependent Translation Initiation, Eukaryotic Translation Initiation, GTP hydrolysis and joining of the 60S ribosomal subunit, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site. Pathway NamePathway Related Protein Cap-dependent Translation InitiationEIF4E; EIF4G1; EIF3K; EIF4EBP1; EIF2S3; EIF2S1A; EIF1AXA; EIF2S1; EIF4H; EIF4A2 Eukaryotic Translation InitiationEIF4A2; EIF4B; EIF4EB; EIF1AX; EIF2S3; EIF3K; EIF1AXA; EIF4A1; EIF2B1; FAUB GTP hydrolysis and joining of the 60S ribosomal subunitEIF4A1; EIF1AXA; EIF4B; EIF4A2; EIF3K; EIF2S1; EIF2S1A; RPL35; EIF1AX; FAUB Gene ExpressionCOX6A1; ZNF785; AIMP2; ESR2A; RBM5; MBD3B; SAP30; ZNF45; TRMT112; POLR3C

3. Metabolism of proteinsTIMM17B; CHCHD4; ZDHHC2; CKAP4; TOMM70A; SEC23IP; YIF1A; ST6GALNAC1.2; EEF1A2; ZNF408 RNA transportNUP210L; TGS1; PAIP1; EIF2B5; SIP1; RAN; TPR; UBE2IB; RAE1; EIF3J Ribosomal scanning and start codon recognitionEIF4H; EIF5 TranslationEEF1A2; EEF1G; EEF1B2; APEH; EIF5; EEF1D; EIF2B1 Protein Function EIF5 has several biochemical functions, for example, GTP binding, GTPase activity, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF5 itself. We selected most functions EIF5 had, and list some proteins which have the same functions with EIF5. You can find most of the proteins on our site. FunctionRelated Protein Function GTP bindingRelated Protein RALAA; ARL10; RAB6B; EIF2B1; RHOGC; ARL3L2; IFT22; RAB11B; LRRK2; RALAB Function GTPase activityRelated Protein RALB; RHOT1; ARL3; RAB44; RAB11AL; GBP6; RABL2A; TBCC; RAB1; RAB40C Function poly(A) RNA bindingRelated Protein AGO2; EIF3G; U2AF1; LARP7; MRPS9; GTPBP4; DDX41; DHX15; FASTKD5; HIST2H4

4. Function protein bindingRelated Protein IL-8; LRCH4; GZMA; CDK15; HSPH1; BRD3; DTX3L; VTI1B; KIAA1958; PSMB10 Function translation factor activity, RNA bindingRelated Protein EIF1; EIF4G1; CPEB1A; EEF1A2; EIF2S3; CPEB4; ABCF1; GTF2H2; EEF1D; CPEB1B Function translation initiation factor activityRelated Protein EIF4EB; MTIF2; GTPBP1; DHX29; EIF4A1; EIF4A1A; EIF3HB; EIF2S1A; EIF2B5; EIF4BB Interacting Protein EIF5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF5 here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF5. DUSP12; EIF1AX; IKBKE; HSPB1; PUM1; ptrB; NRGN; DDX3X; FN1